The study of biocompatibility of magnetic particles using amplification methods
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F15%3APU115587" target="_blank" >RIV/00216305:26310/15:PU115587 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26310/15:PU122751
Result on the web
<a href="http://www.ceitec.eu/a5-abstracts-book-3d/f33102" target="_blank" >http://www.ceitec.eu/a5-abstracts-book-3d/f33102</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
The study of biocompatibility of magnetic particles using amplification methods
Original language description
Magnetic particles for biotechnology applications usually consist of a number of components: magnetic cores are covered with a variety of functionalized low-or high- molecular compounds (polymer layer). Iron oxides and some substances used to stabilize magnetic cores can reduce biocompatibility of the proposed particles; therefore perfectly encapsulated cores are very important for their application. The real-time polymerase chain reaction (qPCR) is very sensitive for the presence a number of chemicals.The increasing inhibitors concentration decreases the amplification efficiency and thus the reaction curve slope decreases. The experiments for the estimation magnetic nano- and microparticles inhibitory effect or biocompatibility respectively on the course of real-time PCR were proposed. The set of magnetic non-porous microspheres covered by different content of carboxyl groups, PEGylated monodisperse magnetic poly(2-hydroxyethyl methacrylate) and poly(glycidyl methacrylate) microspher
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GP13-32840P" target="_blank" >GP13-32840P: The development of encapsulation magnetic nano- and microparticles using real time polymerase chain reaction</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů