Fluorescence anisotropy study of microstructural changes of hyaluronan-cetyltrimethylammonium bromide hydrogel

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F16%3APU120316" target="_blank" >RIV/00216305:26310/16:PU120316 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Fluorescence anisotropy study of microstructural changes of hyaluronan-cetyltrimethylammonium bromide hydrogel
Original language description
This fluorescence study deals with the microstructural changes of physical hydrogel formed by mixing hyaluronan solution with oppositely-charged surfactant cetyltrimethylammonium bromide (CTAB), where micelles of CTAB form directly either physical crosslinks of the hyaluronan hydrogel network. Fluorescence measurements were carried out on this hyaluronan-based hydrogels containing two different fluorescence probes, hydrophobic perylene and hydrophilic one, rhodamine 6G. The excitation and emission spectra, fluorescence intensity, steady-state fluorescence anisotropy and lifetime of probes in the samples were measured. The fluorescence anisotropy values obtained in these experiments were used to estimate a microviscosity of the corresponding hydrogel regions during ageing. It is observed that the hydrophobic domains do not undergo significant structural changes. However, the microviscosity of hydrophilic parts gradually decreases, which indicates some structural changes in the nearby area of rhodamine
Czech name
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Czech description
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Project
<a href="/en/project/LO1211" target="_blank" >LO1211: Materials Research Centre at FCH BUT- Sustainability and Development</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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