Rheological properties of hydrogels based on biopolymer and oppositely charged surfactant

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F17%3APU126032" target="_blank" >RIV/00216305:26310/17:PU126032 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Rheological properties of hydrogels based on biopolymer and oppositely charged surfactant
Original language description
This study is focused on the properties and behaviour of phase-separated hydrogels prepared by interaction of hyaluronan (Hya) with oppositely charged surfactants. Three representatives of surfactants, namely cetyltrimethylammonium bromide, chloride and p-toluensulfonate (CTAB, CTAC, CTAT), were selected for comparison. The method of rheology was used as a crucial one in this research. The fact that the system of Hya-CTAT forms the most rigid hydrogels has been proved. Higher molecular weight of polymer has also direct influence on the volume and stiffness of the hydrogels. The methods of preparation were compared as well. Mixing the stock solutions of entry components appeard to be the most suitable. The final results indicate that studied gels are to a certain extent competitive. Incorporation of hyaluronan into their structure is desirable with respect to its biological activity. This offers a potential usage of these substances in the field of medical applications.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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