Interactions between Cationic Ion Pair Amphiphile Vesicles and Hyaluronan—A Physicochemical Study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F21%3APU141175" target="_blank" >RIV/00216305:26310/21:PU141175 - isvavai.cz</a>
Result on the web
<a href="https://pubs-acs-org.ezproxy.lib.vutbr.cz/doi/abs/10.1021/acs.langmuir.1c00993" target="_blank" >https://pubs-acs-org.ezproxy.lib.vutbr.cz/doi/abs/10.1021/acs.langmuir.1c00993</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acs.langmuir.1c00993" target="_blank" >10.1021/acs.langmuir.1c00993</a>
Alternative languages
Result language
angličtina
Original language name
Interactions between Cationic Ion Pair Amphiphile Vesicles and Hyaluronan—A Physicochemical Study
Original language description
High-resolution ultrasound spectroscopy (HR-US), size and zeta-potential titrations, and isothermal titration calorimetry (ITC) were used to characterize the interactions between hyaluronan and catanionic ion pair amphiphile vesicles composed of hexadecyltrimethylammonium-dodecylsulphate (HTMA-DS), dioctadecyldimethylammonium chloride (DODAC), and cholesterol. In addition to these methods, visual observations were performed with the selected molecular weight of hyaluronan. A very good correlation was obtained between data from size titration, HR-US, and visual observation, which indicated in lower charge ratios the formation of hyaluronan-coated vesicles. On the contrary, at higher charge ratios, coated vesicles disintegrated to a size of around 2000 nm. The intensity of these interactions and the disaggregation were dependent on the molecular weight of hyaluronan. All interactions studied by ITC showed strong exothermic behavior, and these interactions between vesicles and hyaluronan were confirmed from the first addition, independently of the molecular weight of hyaluronan.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10403 - Physical chemistry
Result continuities
Project
<a href="/en/project/GC19-14024J" target="_blank" >GC19-14024J: Hyaluronan-catanionic vesicles complexes – interaction, structure, physical property, and stability</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Langmuir
ISSN
0743-7463
e-ISSN
1520-5827
Volume of the periodical
37
Issue of the periodical within the volume
28
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
8525-8533
UT code for WoS article
000695298500017
EID of the result in the Scopus database
2-s2.0-85110990780