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Interactions between Cationic Ion Pair Amphiphile Vesicles and Hyaluronan—A Physicochemical Study

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F21%3APU141175" target="_blank" >RIV/00216305:26310/21:PU141175 - isvavai.cz</a>

  • Result on the web

    <a href="https://pubs-acs-org.ezproxy.lib.vutbr.cz/doi/abs/10.1021/acs.langmuir.1c00993" target="_blank" >https://pubs-acs-org.ezproxy.lib.vutbr.cz/doi/abs/10.1021/acs.langmuir.1c00993</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1021/acs.langmuir.1c00993" target="_blank" >10.1021/acs.langmuir.1c00993</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Interactions between Cationic Ion Pair Amphiphile Vesicles and Hyaluronan—A Physicochemical Study

  • Original language description

    High-resolution ultrasound spectroscopy (HR-US), size and zeta-potential titrations, and isothermal titration calorimetry (ITC) were used to characterize the interactions between hyaluronan and catanionic ion pair amphiphile vesicles composed of hexadecyltrimethylammonium-dodecylsulphate (HTMA-DS), dioctadecyldimethylammonium chloride (DODAC), and cholesterol. In addition to these methods, visual observations were performed with the selected molecular weight of hyaluronan. A very good correlation was obtained between data from size titration, HR-US, and visual observation, which indicated in lower charge ratios the formation of hyaluronan-coated vesicles. On the contrary, at higher charge ratios, coated vesicles disintegrated to a size of around 2000 nm. The intensity of these interactions and the disaggregation were dependent on the molecular weight of hyaluronan. All interactions studied by ITC showed strong exothermic behavior, and these interactions between vesicles and hyaluronan were confirmed from the first addition, independently of the molecular weight of hyaluronan.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10403 - Physical chemistry

Result continuities

  • Project

    <a href="/en/project/GC19-14024J" target="_blank" >GC19-14024J: Hyaluronan-catanionic vesicles complexes – interaction, structure, physical property, and stability</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Langmuir

  • ISSN

    0743-7463

  • e-ISSN

    1520-5827

  • Volume of the periodical

    37

  • Issue of the periodical within the volume

    28

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    8525-8533

  • UT code for WoS article

    000695298500017

  • EID of the result in the Scopus database

    2-s2.0-85110990780