Digging deeper into the mother-offspring transfer of selenium through human breast milk

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F21%3APU141242" target="_blank" >RIV/00216305:26310/21:PU141242 - isvavai.cz</a>
Result on the web
<a href="https://www-sciencedirect-com.ezproxy.lib.vutbr.cz/science/article/pii/S0889157521000703" target="_blank" >https://www-sciencedirect-com.ezproxy.lib.vutbr.cz/science/article/pii/S0889157521000703</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jfca.2021.103870" target="_blank" >10.1016/j.jfca.2021.103870</a>

Result language
angličtina
Original language name
Digging deeper into the mother-offspring transfer of selenium through human breast milk
Original language description
Selenoprotein P contains most of the selenium in plasma and favours selenium retention in the brain over other organs. Recently, the presence of selenoprotein P in human breast milk has been demonstrated, filling the gap around the mother-offspring transfer of selenium during lactation and through cord serum. In this work, selenometabolites and selenoproteins have been accurately determined in human breast milk and cord and maternal sera. Using a heteroatom tagged proteomic method, twenty mother-child couples were analysed. The mean total concentration in maternal serum was 90 ± 10 ng Se g−1 (1.33 and 1.52-fold higher than that in cord serum and human breast milk, respectively). The concentration of selenoprotein P (ng Se g−1) follows the order: maternal serum (57.1 ± 8.8) > cord serum (33.6 ± 4.2) > breast milk (18.8 ± 5.1). Glutathione peroxidase was mainly transferred by breast milk, selenometabolites were transferred by breast milk and cord serum and selenocystamine was only present in breast milk.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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