Mechanical Properties of Agarose Hydrogels Tuned by Amphiphilic Structures

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F24%3APU151677" target="_blank" >RIV/00216305:26310/24:PU151677 - isvavai.cz</a>

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0927775724016558" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0927775724016558</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.colsurfa.2024.134791" target="_blank" >10.1016/j.colsurfa.2024.134791</a>

Result language

angličtina

Original language name

Mechanical Properties of Agarose Hydrogels Tuned by Amphiphilic Structures

Original language description

Agarose is a biocompatible polysaccharide which is able to form physically cross-linked hydrogels in aqueous dispersion. These materials offer a wide range of applications and are commonly used in the food industry or electrophoresis. Moreover, due to their suitable properties (biocompatibility, high water absorption, porosity), agarose hydrogels have recently also found applications also in drug delivery systems, wound dressing, and extracellular matrix (ECM) modelling. In this paper, a comprehensive rheological characterization of agarose hydrogels with various self-assembled amphiphilic structures (CTAB, TTAB, SDS, Tween 20) acting as simple membrane structure models was performed. The results showed that the presence of surfactants of diverse charge above their critical micellar concentration (CMC) can enhance hydrogel mechanical properties. Moreover, pronounced enhancement was observed for cationic surfactant, and even concentrations below CMC resulted in a higher stiffness of the hydrogel. Therefore, both the electrostatic effect and the amphiphilic structure effect can have a significant impact on the rheological properties on agarose hydrogels. These findings are of a great interest in the field of polymer and surfactants interactions, since agarose is widely considered essentially uncharged. However, it is assumed, that traces of negatively charged groups on the agarose backbone can have a significant impact when interacting with oppositely charged surfactants. Moreover, these findings could be beneficial for better understanding of interaction of polysaccharides (e.g. agarose) and self-assembled amphiphilic structures and can also be considered as a crude model of ECM in which membrane structures are embedded.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10403 - Physical chemistry

Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Colloids and Surfaces A: Physicochemical and Engineering Aspects

ISSN

0927-7757

e-ISSN

1873-4359

Volume of the periodical

700

Issue of the periodical within the volume

1

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

14

Pages from-to

„“-„“

UT code for WoS article

001273754400001

EID of the result in the Scopus database

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