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Comprehensive characterization of natural polysaccharide-based hydrogels with gradient structure in concentration and stiffness

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F24%3APU152485" target="_blank" >RIV/00216305:26310/24:PU152485 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/abs/pii/S0927775724023197" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0927775724023197</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.colsurfa.2024.135455" target="_blank" >10.1016/j.colsurfa.2024.135455</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Comprehensive characterization of natural polysaccharide-based hydrogels with gradient structure in concentration and stiffness

  • Original language description

    Gradient hydrogels are functionally graded biomaterials that over the last decades have garnered significant attention as valuable materials for tissue repair and regeneration. This study elucidates key factors crucially determining the character or pattern of a buoyancy-driven gradient in agarose hydrogels and also provides fundamental information regarding the complex interpretation of the formed gradient hydrogels obtained by the different characterization techniques, including rheology, UV-Vis spectroscopy, FCS, AFM, SEM. The employed techniques were successfully optimized to enhance the understanding of the gradient properties of these hydrogels. Demonstrated results showed that the agarose concentration gradient could be successfully controlled and tailored, which offers a valuable contribution to the design of gradient hydrogel. Moreover, a novel method for determining the average agarose concentration along the gradient axis is presented, improving the precision of gradient characterization. The integration of these approaches significantly enhances the comprehension of the internal structure and properties of gradient materials, contributing to advancements in their understanding and application.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10403 - Physical chemistry

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Colloids and Surfaces A: Physicochemical and Engineering Aspects

  • ISSN

    0927-7757

  • e-ISSN

    1873-4359

  • Volume of the periodical

    704

  • Issue of the periodical within the volume

    135455

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    13

  • Pages from-to

    „“-„“

  • UT code for WoS article

    001333140200001

  • EID of the result in the Scopus database