Bioactive Zirconia-Based Porous Scaffolds For Potential Bone Graft Applications

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F15%3APU114267" target="_blank" >RIV/00216305:26620/15:PU114267 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Bioactive Zirconia-Based Porous Scaffolds For Potential Bone Graft Applications
Original language description
Alumina toughened zirconia (ATZ) / calcium phosphate (Ca-P) composite scaffolds were fabricated via polymer replica technique, the technique that best mimics the macrostructure of trabecular bone. Strong inert core based on ATZ was composed of microsizedzirconia powder bonded by colloidal solution of boehmite. Sintered scaffolds were coated by suspension composed of hydroxyapatite / tricalcium phosphate powders and PVB binder. Scaffolds exhibited well-interconnected structure with pore sizes ranging from 300 to 1200 ?m. Different porosity (50-98%) was achieved by repeating the replication process 1-6 times. The Ca-P coating with a thickness of about 50 ?m was firmly adhered to the ATZ core. Neither of tested materials was cytotoxic. The apatite formation, appeared on the surface of coated scaffolds after immersion in simulated body fluid (SBF) indicated a good bioactivity of the ATZ/Ca-P composite.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Multi-scale Design of Advanced Materials - Conference Proceedings
ISBN
978-80-214-5146-9
ISSN
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e-ISSN
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Number of pages
7
Pages from-to
93-99
Publisher name
Neuveden
Place of publication
Neuveden
Event location
Velké Bílovice
Event date
May 28, 2015
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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