Strength degradation, phase and morphological changes of calcium phosphate scaffolds in acidic environment simulating osteoclastic activity

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F18%3APU129452" target="_blank" >RIV/00216305:26620/18:PU129452 - isvavai.cz</a>
Result on the web
<a href="http://www.esb2018maastricht.org/resources/media/Programme/ESB_2018_Abstract__Proceedings_4.pdf" target="_blank" >http://www.esb2018maastricht.org/resources/media/Programme/ESB_2018_Abstract__Proceedings_4.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Strength degradation, phase and morphological changes of calcium phosphate scaffolds in acidic environment simulating osteoclastic activity
Original language description
Resorbable porous ceramic materials with customized shape are promising category of materials for healing of bone defects with critical size1. Resorption rate of the ceramic structure must correspond to the bone tissue regeneration. The only mechanism of degradation of sintered ceramic materials in a human body is via dissolution under acidic conditions produced by osteoclastic cells2. Dissolution of the ceramics correspond to changes in its mechanical strength. In our research we described structural and mechanical changes of different types of calcium phosphate ceramic materials under acidic conditions simulating osteoclastic activity. Results will help to develop bioceramic scaffolds with controlled resorption rate with good mechanical strength during healing period.
Czech name
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Czech description
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Project
<a href="/en/project/LM2015041" target="_blank" >LM2015041: CEITEC Nano</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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