Biogenic amines modified carbon quantum dots as antibacterial agent

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F19%3APU134908" target="_blank" >RIV/00216305:26620/19:PU134908 - isvavai.cz</a>
Alternative codes found
RIV/62156489:43210/19:43917127
Result on the web
<a href="https://mendelnet.cz/artkey/mnt-201901-0108_Biogenic-amines-modified-carbon-quantum-dots-as-antibacterial-agent.php?back=/magno/mnt/2019/mn1.php?secid=4" target="_blank" >https://mendelnet.cz/artkey/mnt-201901-0108_Biogenic-amines-modified-carbon-quantum-dots-as-antibacterial-agent.php?back=/magno/mnt/2019/mn1.php?secid=4</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Biogenic amines modified carbon quantum dots as antibacterial agent
Original language description
An alternative to conventional way is needed to treat multiple drug resistant bacteria. In this work, four different amine modified carbon quantum dots (CQDs) were obtained by microwave irradiation treatment. The four different biogenic amines (spermidine, putrescine, cadaverine, and histamine) as capping agent and citric acid as a carbon precursor were used. Prepared CQDs were evaluated for their antibacterial activity against three common pathogenic bacteria (Escherichia coli, Klebsiella pneumonia, Staphylococcus aureus), and the growth curves were modeled. The CQDs showed a strong broad-spectrum antibacterial activity. The bactericidal activity was linked to their specific surface chemistry and caused bacterial death, which was due to the electrostatic interactions between protonated CQDs and the lipids of the bacterial cell membrane. The biocompatibility of CQDs was tested in HBL100 and HEK293 cell lines and low or absence of toxicity was indicated.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
MendelNet 2019 Proceedings of 26th International PhD Students Conference
ISBN
978-80-7509-688-3
ISSN
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e-ISSN
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Number of pages
5
Pages from-to
569-573
Publisher name
Mendel University in Brno
Place of publication
Neuveden
Event location
Brno
Event date
Nov 6, 2019
Type of event by nationality
CST - Celostátní akce
UT code for WoS article
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