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A non-enzymatic sensor for sensitive determination of H2O2 using biomimetic nanocomposite

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F19%3APU134918" target="_blank" >RIV/00216305:26620/19:PU134918 - isvavai.cz</a>

  • Alternative codes found

    RIV/62156489:43210/19:43917131

  • Result on the web

    <a href="https://mendelnet.cz/artkey/mnt-201901-0113_A-non-enzymatic-sensor-for-sensitive-determination-of-H-sub-2-sub-O-sub-2-sub-using-biomimetic-nanocomposite.php?back=/magno/mnt/2019/mn1.php?secid=4" target="_blank" >https://mendelnet.cz/artkey/mnt-201901-0113_A-non-enzymatic-sensor-for-sensitive-determination-of-H-sub-2-sub-O-sub-2-sub-using-biomimetic-nanocomposite.php?back=/magno/mnt/2019/mn1.php?secid=4</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    A non-enzymatic sensor for sensitive determination of H2O2 using biomimetic nanocomposite

  • Original language description

    Hydrogen peroxide (H2O2), as a critical secondary messenger, is important for in vitro and in vivo study. In addition, it is of great significance in monitoring the biological condition under chemical oxidative stress. A non-enzymatic sensor was developed for the detection and monitoring of H2O2 using a nanocomposite (NC). The NC is prepared and modified by using multi-walled carbon nanotubes and tris(2,2’-bipyridyl) copper(II) dichloride complex acts as a mediator. The electrochemical techniques like cyclic voltammetry and chrono-amperometry were used to study the electrochemical behaviour of H2O2 at the developed electrode. The reduction peak of H2O2 shifts to less negative potential with increasing the reducing current at the developed electrode. The calibration curve of the proposed sensor was plotted using chrono-amperometry at −0.1 V as applied potential with stepwise addition of H2O2. The developed sensor has high stability and able to detect H2O2 with a high sensitivity and repeatability. The linear range was found to be 2.4–33.0 µg/ml. Furthermore, the limit of detection and the limit of quantification were 0.7 µg/ml and 2.4 µg/ml, respectively. The reproducibility of the prepared sensor was evaluated by calculating the RSD% = 7.2.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    10406 - Analytical chemistry

Result continuities

  • Project

    <a href="/en/project/LQ1601" target="_blank" >LQ1601: CEITEC 2020</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    MendelNet 2019 Proceedings of 26th International PhD Students Conference

  • ISBN

    978-80-7509-688-3

  • ISSN

  • e-ISSN

  • Number of pages

    6

  • Pages from-to

    585-590

  • Publisher name

    Mendel University in Brno

  • Place of publication

    Neuveden

  • Event location

    Brno

  • Event date

    Nov 6, 2019

  • Type of event by nationality

    CST - Celostátní akce

  • UT code for WoS article