A non-enzymatic sensor for sensitive determination of H2O2 using biomimetic nanocomposite
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F19%3APU134918" target="_blank" >RIV/00216305:26620/19:PU134918 - isvavai.cz</a>
Alternative codes found
RIV/62156489:43210/19:43917131
Result on the web
<a href="https://mendelnet.cz/artkey/mnt-201901-0113_A-non-enzymatic-sensor-for-sensitive-determination-of-H-sub-2-sub-O-sub-2-sub-using-biomimetic-nanocomposite.php?back=/magno/mnt/2019/mn1.php?secid=4" target="_blank" >https://mendelnet.cz/artkey/mnt-201901-0113_A-non-enzymatic-sensor-for-sensitive-determination-of-H-sub-2-sub-O-sub-2-sub-using-biomimetic-nanocomposite.php?back=/magno/mnt/2019/mn1.php?secid=4</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
A non-enzymatic sensor for sensitive determination of H2O2 using biomimetic nanocomposite
Original language description
Hydrogen peroxide (H2O2), as a critical secondary messenger, is important for in vitro and in vivo study. In addition, it is of great significance in monitoring the biological condition under chemical oxidative stress. A non-enzymatic sensor was developed for the detection and monitoring of H2O2 using a nanocomposite (NC). The NC is prepared and modified by using multi-walled carbon nanotubes and tris(2,2’-bipyridyl) copper(II) dichloride complex acts as a mediator. The electrochemical techniques like cyclic voltammetry and chrono-amperometry were used to study the electrochemical behaviour of H2O2 at the developed electrode. The reduction peak of H2O2 shifts to less negative potential with increasing the reducing current at the developed electrode. The calibration curve of the proposed sensor was plotted using chrono-amperometry at −0.1 V as applied potential with stepwise addition of H2O2. The developed sensor has high stability and able to detect H2O2 with a high sensitivity and repeatability. The linear range was found to be 2.4–33.0 µg/ml. Furthermore, the limit of detection and the limit of quantification were 0.7 µg/ml and 2.4 µg/ml, respectively. The reproducibility of the prepared sensor was evaluated by calculating the RSD% = 7.2.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
<a href="/en/project/LQ1601" target="_blank" >LQ1601: CEITEC 2020</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
MendelNet 2019 Proceedings of 26th International PhD Students Conference
ISBN
978-80-7509-688-3
ISSN
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e-ISSN
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Number of pages
6
Pages from-to
585-590
Publisher name
Mendel University in Brno
Place of publication
Neuveden
Event location
Brno
Event date
Nov 6, 2019
Type of event by nationality
CST - Celostátní akce
UT code for WoS article
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