Chemical Microrobots as Self-Propelled Microbrushes against Dental Biofilm
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F20%3APU138406" target="_blank" >RIV/00216305:26620/20:PU138406 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22310/20:43920513 RIV/60461373:22330/20:43920513
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S2666386420301922" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2666386420301922</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.xcrp.2020.100181" target="_blank" >10.1016/j.xcrp.2020.100181</a>
Alternative languages
Result language
angličtina
Original language name
Chemical Microrobots as Self-Propelled Microbrushes against Dental Biofilm
Original language description
Mouths offer the perfect environments for microbial cell formation, promoting the growth of biofilms, for example, on teeth. Dental biofilm exhibits strong resistance to antibiotics and is a cause of many dental diseases. Common strategies for dental biofilm removal involve the addition of high concentrations of hydrogen peroxide (H2O2), which increases tooth sensitivity, or mechanical procedures. Here, we report a different approach based on self-propelled micromachines with high antibacterial activity for the degradation of dental biofilm. Such microrobots use low concentrations of fuel for their propulsion, and they achieve an efficient dental biofilm disruption in only 5 min of treatment. Moreover, these microrobots are biocompatible with epidermal and organ cells and may stimulate the immune system to fight against microbial infection. This approach of exploiting the active motion of bubble-propelled catalytic micromachines for oral biofilm disruption may open the door for more efficient and sophisticated treatments in dentistry.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30404 - Biomaterials (as related to medical implants, devices, sensors)
Result continuities
Project
<a href="/en/project/LL2002" target="_blank" >LL2002: Autonomous Smart Swarming Microswimmers</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cell Reports Physical Science
ISSN
2666-3864
e-ISSN
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Volume of the periodical
1
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
18
Pages from-to
1-18
UT code for WoS article
000658752300008
EID of the result in the Scopus database
2-s2.0-85099015099