2D transition metal dichalcogenide nanomaterial-based miRNA biosensors
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F21%3APU141231" target="_blank" >RIV/00216305:26620/21:PU141231 - isvavai.cz</a>
Alternative codes found
RIV/62156489:43210/21:43919730
Result on the web
<a href="https://doi.org/10.1016/j.apmt.2021.101043" target="_blank" >https://doi.org/10.1016/j.apmt.2021.101043</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.apmt.2021.101043" target="_blank" >10.1016/j.apmt.2021.101043</a>
Alternative languages
Result language
angličtina
Original language name
2D transition metal dichalcogenide nanomaterial-based miRNA biosensors
Original language description
MicroRNAs (miRNAs) are short oligonucleotides responsible for the regulation of basic cellular mechanisms. The detection of miRNA in clinical practice involves conventional methods (northern blot, microarrays, RT-qPCR) that provide good sensitivity and specificity. However, their high cost and time-consuming nature prevent their implementation as routine analysis. Biosensors, as alternative detection platforms, can compensate for these flaws, providing good sensitivity and specificity as well as low prices per assay and fast generation of results; therefore, biosensors may ultimately replace conventional methods. The fast progress in nanotechnology has created new prospects in biosensor fabrication, presenting a selection of nanomaterials compatible for the detection of various biomolecules. Two-dimensional transition metal dichalcogenides (2D TMDCs) demonstrate promising qualities, such as biocompatibility, a large surface area for detection and diverse possibilities for altering electrochemical and optical properties; hence, an improved detection performance can be achieved. In this review, the recent progress in biosensor fabrication for detecting miRNAs based on 2D TMDCs is summarized and supported by the basic understanding of miRNA biosynthetic pathways and detection methods. Additionally, insight into the structure and properties of TMDCs will be disclosed as well as suitable methods for their synthesis and the mechanisms for tuning their properties.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Applied Materials Today
ISSN
2352-9407
e-ISSN
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Volume of the periodical
23
Issue of the periodical within the volume
101043
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
23
Pages from-to
„1“-„23 “
UT code for WoS article
000667468400034
EID of the result in the Scopus database
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