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SiO2-decorated Parylene C micropillars designed to probe cellular force

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F21%3APU142299" target="_blank" >RIV/00216305:26620/21:PU142299 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    SiO2-decorated Parylene C micropillars designed to probe cellular force

  • Original language description

    Living cells sense and respond to mechanical signals through specific mechanisms that generate traction force. The quantification of cell forces using micropillars can be limited by micropillar stiffness which depends on Young´s modulus of material and aspect ratio of pillars, technological limitation of the fabrication, and microcontact printing of proteins. The work shows “top-down” fabrication of a highly ordered array of SiO2/Parylene C micropillars standing on the Si substrate that can be used as a probe to quantify the force generated from cells.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    20501 - Materials engineering

Result continuities

  • Project

    <a href="/en/project/GJ19-04270Y" target="_blank" >GJ19-04270Y: Real-time mapping of cellular traction forces</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů