Plasma-coated PCL scaffolds with immobilized platelet-rich plasma enhance the wound healing in diabetics mice

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F22%3APU145065" target="_blank" >RIV/00216305:26620/22:PU145065 - isvavai.cz</a>
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1002/ppap.202200032" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/ppap.202200032</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/ppap.202200032" target="_blank" >10.1002/ppap.202200032</a>

Result language
angličtina
Original language name
Plasma-coated PCL scaffolds with immobilized platelet-rich plasma enhance the wound healing in diabetics mice
Original language description
COOH plasma polymer layers deposited onto polycaprolactone (PCL) nanofibers by plasma polymerization of CO2 and C2H4 in the Ar atmosphere were obtained and tested for diabetic wound healing. Simply by changing the deposition time, very different morphologies of coated PCL nanofibers were achieved. In vivo tests revealed that by applying modified nanofibers for 10 days, wound healing accelerated by 32.1%. Compared to a controlled wound characterized by an acute inflammatory process, wounds covered with nanofibers with platelet-rich plasma demonstrated complete healing with a high percentage of collagen fibers on Day 19.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10305 - Fluids and plasma physics (including surface physics)

Project
<a href="/en/project/LM2018110" target="_blank" >LM2018110: CzechNanoLab research infrastructure</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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