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Imaging of Biological Tissues

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F22%3APU147827" target="_blank" >RIV/00216305:26620/22:PU147827 - isvavai.cz</a>

  • Result on the web

    <a href="https://link.springer.com/chapter/10.1007/978-3-031-14502-5_6" target="_blank" >https://link.springer.com/chapter/10.1007/978-3-031-14502-5_6</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/978-3-031-14502-5_6" target="_blank" >10.1007/978-3-031-14502-5_6</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Imaging of Biological Tissues

  • Original language description

    Laser-Induced Breakdown Spectroscopy (LIBS) has established its position as a method for the analysis of biological samples. We aim to introduce the benefits of LIBS for the qualitative elemental imaging of tissues. The state-of-the-art instrumentation enables elemental imaging of sample surfaces with a high resolution (down to micro-scale) on a large scale (up to a whole-slide image), i.e., megapixel imaging of the distribution of investigated elements. The implementation of this promising tool to the analytical pipeline in various fields (from developmental biology to clinical research) is discussed. The typical interpretation of LIBS results through basic spectroscopic algorithms and machine learning is dissected. The chapter reviews recent advances of LIBS namely in soft and hard tissue analyses when the detection of endogenous and exogenous elements (major and trace metals) is concerned. The comparison to other elemental imaging methods (namely Laser Ablation Inductively Coupled Plasma Mass Spectrometry) is given. Finally, future perspectives and development of LIBS bioimaging is suggested.

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

  • OECD FORD branch

    10406 - Analytical chemistry

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Laser-Induced Breakdown Spectroscopy in Biological, Forensic and Materials Sciences

  • ISBN

    978-3-031-14502-5

  • Number of pages of the result

    26

  • Pages from-to

    „“-„“

  • Number of pages of the book

    313

  • Publisher name

    Neuveden

  • Place of publication

    Neuveden

  • UT code for WoS chapter