Challenges in the laser ablation of soft tissues

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F20%3APU137841" target="_blank" >RIV/00216305:26620/20:PU137841 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26620/20:PU137847
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Challenges in the laser ablation of soft tissues
Original language description
The main benefit of laser-induced breakdown spectroscopy (LIBS) in elemental imaging of biological samples is namely the capability to provide large scale analysis (i.e. whole slide imaging). Thus, LIBS may serve as a complementary technique providing a fast scan of the sample and guiding the researcher in further analysis across applications, incl. cancer research. However, elemental imaging of biological samples still remains a challenging task, mainly due to the soft nature of biological tissues and its heterogeneous composition. [1] Laser-tissue interaction is a complex phenomenon that is simultaneously influenced by several parameters (laser energy, spot size, ambient atmosphere, etc.). Thus, in our work, we have suggested a way how to prepare and optimize soft-tissue samples in order to get the best possible analytical signal response. Concurrently, we aim to stick to the histological preparation of the sample while it is a golden standard used in clinical research. Therefore, we only used paraf
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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