Insight into peculiar adhesion of cells to plasma-chemically prepared multifunctional "amino-glue" surfaces
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F23%3APU148450" target="_blank" >RIV/00216305:26620/23:PU148450 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/23:00131232 RIV/44555601:13440/23:43897694
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1002/ppap.202200157" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/ppap.202200157</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/ppap.202200157" target="_blank" >10.1002/ppap.202200157</a>
Alternative languages
Result language
angličtina
Original language name
Insight into peculiar adhesion of cells to plasma-chemically prepared multifunctional "amino-glue" surfaces
Original language description
Plasma polymers (PPs) can easily modify material surfaces to improve their bio-applicability due to match-made surface-free energy and functionality. However, cell adhesion to PPs typically composed of various functional groups has not yet been fully understood. We explain the origin of strong resistance to trypsin treatment previously noted for nonendothelial cells on amine PPs. It is caused mainly by nonspecific adhesion of negatively charged parts of transmembrane proteins to the positively charged amine PP surface, enabled by thin glycocalyx. However, endothelial cells are bound primarily by their thick, negatively charged glycocalyx and sporadically by integrins in kinetic traps, both cleaved by trypsin. Cell scratching by atomic force microscopy tip confirmed the correlation of trypsin resistance to the strength of cell adhesion.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10300 - Physical sciences
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Plasma Processes and Polymers
ISSN
1612-8850
e-ISSN
1612-8869
Volume of the periodical
20
Issue of the periodical within the volume
6
Country of publishing house
DE - GERMANY
Number of pages
15
Pages from-to
1-15
UT code for WoS article
000941082700001
EID of the result in the Scopus database
2-s2.0-85149387367