Carboxyl-anhydride and amine plasma coating of PCL nanofibers to improve their bioactivity
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F17%3A00097544" target="_blank" >RIV/00216224:14740/17:00097544 - isvavai.cz</a>
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0264127517306469" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0264127517306469</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.matdes.2017.06.057" target="_blank" >10.1016/j.matdes.2017.06.057</a>
Alternative languages
Result language
angličtina
Original language name
Carboxyl-anhydride and amine plasma coating of PCL nanofibers to improve their bioactivity
Original language description
The plasmamodification of biodegradable nanofibers is of great interest for improvement of their biocompatibility. However, there are no systematic studies regarding the influence of plasma polymer deposition onto the surface of nanofibers to improve cell adhesion. In the present study, homogenous and reproducible modification of polycaprolactone (PCL) nanofibers by amine and carboxyl/anhydride groupswas achieved. The concentration of amines NH2/C and C(O)O contribution were up to 2.9 and 14.1%, respectively. Regardless the plasma conditions, the deposition of amine and carboxyl-anhydride plasma coatings onto the PCL nanofibers sufficiently improved the cell adhesion and viability, as was evidenced by microscopy observations and ATP assay results. It should be emphasized that the deposition of negatively charged carboxyl-anhydride coatings resulted in slightly better cell adhesion compared to the positively charged amine plasma coatings, unlike the widespread opinion that COOH modification has less effect on myoblasts adhesion. (C) 2017 Elsevier Ltd. All rights reserved.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10600 - Biological sciences
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
MATERIALS & DESIGN
ISSN
0264-1275
e-ISSN
—
Volume of the periodical
132
Issue of the periodical within the volume
October
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
257-265
UT code for WoS article
000408688300028
EID of the result in the Scopus database
2-s2.0-85022230180