Surface modification strategies and the functional mechanisms of gold nanozyme in biosensing and bioassay

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F23%3APU148479" target="_blank" >RIV/00216305:26620/23:PU148479 - isvavai.cz</a>

Alternative codes found

RIV/62156489:43210/23:43923419

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S2590006423001163" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2590006423001163</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.mtbio.2023.100656" target="_blank" >10.1016/j.mtbio.2023.100656</a>

Result language

angličtina

Original language name

Surface modification strategies and the functional mechanisms of gold nanozyme in biosensing and bioassay

Original language description

Gold nanozymes (GNZs) have been widely used in biosensing and bioassay due to their interesting catalytic activities that enable the substitution of natural enzyme. This review explains different catalytic activities of GNZs that can be achieved by applying different modifications to their surface. The role of Gold nanoparticles (GNPs) in mimicking oxidoreductase, helicase, phosphatase were introduced. Moreover, the effect of surface properties and modifications on each catalytic activity was thoroughly discussed. The application of GNZs in biosensing and bioassay was classified in five categories based on the combination of the enzyme like activities and enhancing/ inhibition of the catalytic activities in presence of the target analyte/s that is realized by proper surface modification engineering. These categories include catalytic activity enhancer, reversible catalytic activity inhibitor, binding selectivity enhancer, agglomeration base, and multienzyme like activity, which are explained and exemplified in this review. It also gives examples of those modifications that enable the application of GNZs for in vivo biosensing and bioassays.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

20601 - Medical engineering

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Materials Today Bio

ISSN

2590-0064

e-ISSN

—

Volume of the periodical

20

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

16

Pages from-to

„“-„“

UT code for WoS article

001002673700001

EID of the result in the Scopus database

2-s2.0-85159152479