Immunochemical Applications Utilizing Laser-Induced Breakdown Spectroscopy Detection
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F26%3A0199443" target="_blank" >RIV/00216305:26620/26:0199443 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/25:00144353
Result on the web
<a href="https://link.springer.com/chapter/10.1007/978-3-031-85975-5_11" target="_blank" >https://link.springer.com/chapter/10.1007/978-3-031-85975-5_11</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-031-85975-5_11" target="_blank" >10.1007/978-3-031-85975-5_11</a>
Alternative languages
Result language
angličtina
Original language name
Immunochemical Applications Utilizing Laser-Induced Breakdown Spectroscopy Detection
Original language description
Immunochemistry specifically detects or visualizes biologically important analytes, such as disease biomarkers or pathogens, employing various detection techniques. This can be done by employing label-based assays for indirect detection of the analytes. The labels for immunochemical methods, typically with luminescence or enzymatic properties, are selected to allow a simple and fast detection, high accuracy, and reproducibility of the measurements. In this chapter, immunochemical methodology based on laser-induced breakdown spectroscopy (LIBS) detection is mainly discussed in comparison with other commonly used techniques based on luminescence or color change monitoring. Being a multielemental analytical technique, LIBS allows for the differentiation of the labels based on their elemental composition with no need for specific label properties (e.g., luminescence) while maintaining the information on the distribution of other valuable constituents. For the sake of complementarity, laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) as a detection technique for immunochemical methods is also included in the chapter as it serves not only as a reference for the tag-LIBS technique. With the continual advancement of the instrumentation of both techniques, the possibility of a tandem analysis by tag-LIBS and LA-ICP-MS might be explored in the future.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
<a href="/en/project/GA22-27580S" target="_blank" >GA22-27580S: Laser spectroscopy for nanometal-based label assays and imaging</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Laser-Induced Breakdown Spectroscopy in Biological, Forensic and Materials Sciences
ISBN
9783031859748
Number of pages of the result
26
Pages from-to
331-356
Number of pages of the book
559
Publisher name
Springer Nature Switzerland
Place of publication
Cham
UT code for WoS chapter
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