Low-temperature sintered boron-doped S53P4 bioactive glass scaffolds fabricated by robocasting
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F26%3A0199461" target="_blank" >RIV/00216305:26620/26:0199461 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1111/jace.70292" target="_blank" >https://doi.org/10.1111/jace.70292</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/jace.70292" target="_blank" >10.1111/jace.70292</a>
Alternative languages
Result language
angličtina
Original language name
Low-temperature sintered boron-doped S53P4 bioactive glass scaffolds fabricated by robocasting
Original language description
This study investigates boron-doped S53P4 bioactive glass (BG) scaffolds fabricated via robocasting in the context of bone regeneration strategies by comparing their mechanical performance and bioactive behavior to undoped S53P4 BG scaffolds. Three-dimensional scaffolds with grid-like macro architectures were fabricated using gelatin-based composite inks containing S53P4 BG and 10 wt.% boron-doped S53P4 BG (S53P4_10B). The scaffolds were sintered at optimized temperatures (900 degrees C for S53P4 and 615 degrees C for S53P4_10B), resulting in an average volumetric shrinkage of 33 vol%. Both scaffold types exhibited high porosity (similar to 71%) with pore sizes of 584 +/- 7 mu m (S53P4) and 608 +/- 25 mu m (S53P4_10B). Compressive strength values of 3.3 +/- 1.7 MPa and 1.5 +/- 0.4 MPa were respectively measured for S53P4 and for S53P4_10B BG scaffolds. Soaking in simulated body fluid for 14 days resulted in complete surface coverage with calcium-phosphate-rich phases, indicating high bioactivity. Antibacterial tests revealed that while crystallization reduced the inhibition zone of S53P4 scaffolds, S53P4_10B scaffolds exhibited significant antibacterial activity against E. coli and S. aureus. Cytocompatibility tests using MG-63 and ST-2 cell lines confirmed that scaffold extracts at concentrations
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20504 - Ceramics
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of the American Ceramic Society
ISSN
0002-7820
e-ISSN
1551-2916
Volume of the periodical
1
Issue of the periodical within the volume
109
Country of publishing house
US - UNITED STATES
Number of pages
20
Pages from-to
1-20
UT code for WoS article
001589426700001
EID of the result in the Scopus database
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