Retrograde Oxygen Persufflation of Kidney - Experiment on an Animal
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F16%3A10330073" target="_blank" >RIV/00669806:_____/16:10330073 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21460/16:00303672 RIV/00216208:11140/16:10330073
Result on the web
<a href="http://dx.doi.org/10.21873/invivo.10997" target="_blank" >http://dx.doi.org/10.21873/invivo.10997</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.21873/invivo.10997" target="_blank" >10.21873/invivo.10997</a>
Alternative languages
Result language
angličtina
Original language name
Retrograde Oxygen Persufflation of Kidney - Experiment on an Animal
Original language description
Aim: There is still a lack of organs for transplantation purposes. In the field of kidney and liver transplantation, one available solution is the use of organs from so-called marginal donors. These donors can be e.g. non-heart-beating donors. In these cases, perfusion and preservation of organs intended for transplantation is generally more difficult. Retrograde oxygen persufflation (ROP) may be a possible solution to this issue. This method is based on retrograde perfusion by oxygen through the renal vein thus reconditioning the organ. Materials and Methods: We operated on 10 animals (porcine models). Ischemic injury of the right kidney was simulated in all animals . In group A (N=5), kidneys were perfused with retrograde oxygen persufflation after explantation . In group B (N=5), kidneys were perfused intrarterially as in usual clinical practice. After perfusion all kidneys were transplanted to the original donor animal. Quality of graft restitution was evaluated by urea level taken from the renal vein and by histopathological analysis after explantation. Results: We found no statistically significant differences between groups A and B in urea levels after transplantation, nor did we find any significant differences in quality of kidney parenchyma restoration between these groups. Conclusion: Retrograde oxygen persufflation is able to protect and restore kidney parenchyma.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FJ - Surgery including transplantology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
In Vivo
ISSN
0258-851X
e-ISSN
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Volume of the periodical
30
Issue of the periodical within the volume
6
Country of publishing house
GR - GREECE
Number of pages
5
Pages from-to
801-805
UT code for WoS article
000392926200011
EID of the result in the Scopus database
2-s2.0-84994385696