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Retrograde Oxygen Persufflation of Kidney - Experiment on an Animal

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F16%3A10330073" target="_blank" >RIV/00669806:_____/16:10330073 - isvavai.cz</a>

  • Alternative codes found

    RIV/68407700:21460/16:00303672 RIV/00216208:11140/16:10330073

  • Result on the web

    <a href="http://dx.doi.org/10.21873/invivo.10997" target="_blank" >http://dx.doi.org/10.21873/invivo.10997</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.21873/invivo.10997" target="_blank" >10.21873/invivo.10997</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Retrograde Oxygen Persufflation of Kidney - Experiment on an Animal

  • Original language description

    Aim: There is still a lack of organs for transplantation purposes. In the field of kidney and liver transplantation, one available solution is the use of organs from so-called marginal donors. These donors can be e.g. non-heart-beating donors. In these cases, perfusion and preservation of organs intended for transplantation is generally more difficult. Retrograde oxygen persufflation (ROP) may be a possible solution to this issue. This method is based on retrograde perfusion by oxygen through the renal vein thus reconditioning the organ. Materials and Methods: We operated on 10 animals (porcine models). Ischemic injury of the right kidney was simulated in all animals . In group A (N=5), kidneys were perfused with retrograde oxygen persufflation after explantation . In group B (N=5), kidneys were perfused intrarterially as in usual clinical practice. After perfusion all kidneys were transplanted to the original donor animal. Quality of graft restitution was evaluated by urea level taken from the renal vein and by histopathological analysis after explantation. Results: We found no statistically significant differences between groups A and B in urea levels after transplantation, nor did we find any significant differences in quality of kidney parenchyma restoration between these groups. Conclusion: Retrograde oxygen persufflation is able to protect and restore kidney parenchyma.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FJ - Surgery including transplantology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    In Vivo

  • ISSN

    0258-851X

  • e-ISSN

  • Volume of the periodical

    30

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    GR - GREECE

  • Number of pages

    5

  • Pages from-to

    801-805

  • UT code for WoS article

    000392926200011

  • EID of the result in the Scopus database

    2-s2.0-84994385696