Relation between TGF-ß 1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F10%3A00100917" target="_blank" >RIV/00843989:_____/10:00100917 - isvavai.cz</a>

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Relation between TGF-ß 1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus

Original language description

Therapy of posthemorrhagic hydrocephalus (PHH) by using ventriculo-peritoneal drainage bears considerable rate of complications and remains a challenge in premature newborns. The role of endoscopic third ventriculostomy (ETV) in these patients is unclear, through obstruction is proved in some patients with PHH.TGF ? 1 release into the CSF in time of primary bleeding is suggested as one of possible pathophysiologic reasons of PHH formation. Relation between TGF ?1 levels and ETV success rate has not beenreported yet. The aim of our study is to detect group of patients, according to the levels of TGF ?1, who have MRI proved obstruction hydrocefalus without participation of hyporesorption ? so that we can expect success of ETV. MethodsWe followed 29 premature newborns with PHH during 2005-2007, all of them treated by Ommaya reservoir implantation and repeated taps with TGF ?1 levels examination. In case of persisting hydrocephalus MRI was performed. In 16 patients with proved

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

—

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Child's nervous system

ISSN

0256-7040

e-ISSN

—

Volume of the periodical

26

Issue of the periodical within the volume

3

Country of publishing house

DE - GERMANY

Number of pages

9

Pages from-to

—

UT code for WoS article

000274500800009

EID of the result in the Scopus database

—