Immunological and autoimmune considerations of Autism Spectrum Disorders

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F13%3AE0104040" target="_blank" >RIV/00843989:_____/13:E0104040 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.jaut.2013.05.005" target="_blank" >http://dx.doi.org/10.1016/j.jaut.2013.05.005</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jaut.2013.05.005" target="_blank" >10.1016/j.jaut.2013.05.005</a>

Result language
angličtina
Original language name
Immunological and autoimmune considerations of Autism Spectrum Disorders
Original language description
Autism Spectrum Disorders (ASD) are a group of heterogeneous neurodevelopmental conditions presenting in early childhood with a prevalence ranging from 0.7% to 2.64%. Social interaction and communication skills are impaired and children often present with unusual repetitive behavior. The condition persists for life with major implications for the individual, the family and the entire health care system. While the etiology of ASD remains unknown, various clues suggest a possible association with alteredimmune responses and ASD. Inflammation in the brain and CNS has been reported by several groups with notable microglia activation and increased cytokine production in postmortem brain specimens of young and old individuals with ASD. Moreover several laboratories have isolated distinctive brain and CNS reactive antibodies from individuals with ASD. Large population based epidemiological studies have established a correlation between ASD and a family history of autoimmune diseases, associa
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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