Lymphangiogenesis and its correlation with the VEGF expression and the sentinel lymph node in cutaneous melanomas

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F14%3AE0104072" target="_blank" >RIV/00843989:_____/14:E0104072 - isvavai.cz</a>

Alternative codes found

RIV/61988987:17110/14:A1501BTG

Result on the web

<a href="http://dx.doi.org/10.1155/2014/372979" target="_blank" >http://dx.doi.org/10.1155/2014/372979</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2014/372979" target="_blank" >10.1155/2014/372979</a>

Result language

angličtina

Original language name

Lymphangiogenesis and its correlation with the VEGF expression and the sentinel lymph node in cutaneous melanomas

Original language description

The aim of the study is to evaluate the density of intratumoral and peritumoral lymphatic vessels in primary cutaneous melanomas and to assess their correlation with the status of sentinel lymph nodes and the VEGF expression in tumor cells and stromal cells. A total of 40 patients were enrolled in the study: the melanomas were radically excised with the extirpation of the sentinel lymph node. The study subjects were divided into two groups: 20 cases with positive and 20 cases with negative sentinel lymph node results. The density of lymphatic vessels was evaluated by the antibody D2-40 and the VEGF expression was investigated in the semiquantitative way. The VEGF expression in melanoma cells and the stromal cells was negative to variable positive at both SLN negative and SLN positive patients in all pT stages. In the group of SLN positive patients, the density of intratumoral lymphatic vessels was low up to moderate, while it was observed to be absent, somewhere on the low level in the

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

BioMed research international

ISSN

2314-6133

e-ISSN

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Volume of the periodical

2014

Issue of the periodical within the volume

n. Article ID 372979

Country of publishing house

US - UNITED STATES

Number of pages

6

Pages from-to

"p. 1-6"

UT code for WoS article

000338555200001

EID of the result in the Scopus database

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