Lymphangiogenesis and its correlation with the VEGF expression and the sentinel lymph node in cutaneous melanomas
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F14%3AE0104072" target="_blank" >RIV/00843989:_____/14:E0104072 - isvavai.cz</a>
Alternative codes found
RIV/61988987:17110/14:A1501BTG
Result on the web
<a href="http://dx.doi.org/10.1155/2014/372979" target="_blank" >http://dx.doi.org/10.1155/2014/372979</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2014/372979" target="_blank" >10.1155/2014/372979</a>
Alternative languages
Result language
angličtina
Original language name
Lymphangiogenesis and its correlation with the VEGF expression and the sentinel lymph node in cutaneous melanomas
Original language description
The aim of the study is to evaluate the density of intratumoral and peritumoral lymphatic vessels in primary cutaneous melanomas and to assess their correlation with the status of sentinel lymph nodes and the VEGF expression in tumor cells and stromal cells. A total of 40 patients were enrolled in the study: the melanomas were radically excised with the extirpation of the sentinel lymph node. The study subjects were divided into two groups: 20 cases with positive and 20 cases with negative sentinel lymph node results. The density of lymphatic vessels was evaluated by the antibody D2-40 and the VEGF expression was investigated in the semiquantitative way. The VEGF expression in melanoma cells and the stromal cells was negative to variable positive at both SLN negative and SLN positive patients in all pT stages. In the group of SLN positive patients, the density of intratumoral lymphatic vessels was low up to moderate, while it was observed to be absent, somewhere on the low level in the
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BioMed research international
ISSN
2314-6133
e-ISSN
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Volume of the periodical
2014
Issue of the periodical within the volume
n. Article ID 372979
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
"p. 1-6"
UT code for WoS article
000338555200001
EID of the result in the Scopus database
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