Choices of stent and cerebral protection in the ongoing ACST-2 trial: a descriptive study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F17%3AE0106956" target="_blank" >RIV/00843989:_____/17:E0106956 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.ejvs.2016.12.034" target="_blank" >http://dx.doi.org/10.1016/j.ejvs.2016.12.034</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ejvs.2016.12.034" target="_blank" >10.1016/j.ejvs.2016.12.034</a>

Result language

angličtina

Original language name

Choices of stent and cerebral protection in the ongoing ACST-2 trial: a descriptive study

Original language description

Objective/Background: Several plaque and lesion characteristics have been associated with an increased risk for procedural stroke during or shortly after carotid artery stenting (CAS). While technical advancements in stent design and cerebral protection devices (CPD) may help reduce the procedural stroke risk, and anatomy remains important, tailoring stenting procedures according to plaque and lesion characteristics might be a useful strategy in reducing stroke associated with CAS. In this descriptive report of the ongoing Asymptomatic Carotid Surgery Trial-2 (ACST-2), it was assessed whether choice for stent and use or type of CPD was influenced by plaque and lesion characteristics. Methods: Trial patients who underwent CAS between 2008 and 2015 were included in this study. Chi-square statistics were used to study the effects of plaque echolucency, ipsilateral preocclusive disease (90–99%), and contralateral high-grade stenosis (>50%) or occlusion of the carotid artery on interventionalists’ choice for stent and CPD. Differences in treatment preference between specialties were also analysed. Results: In this study, 831 patients from 88 ACST-2 centres were included. Almost all procedures were performed by either interventional radiologists (50%) or vascular surgeons (45%). Plaque echolucency, ipsilateral preocclusive disease (90–99%), and significant contralateral stenosis (>50%) or occlusion did not affect the choice of stent or either the use of cerebral protection and type of CPD employed (i.e., filter/flow reversal). Vascular surgeons used a CPD significantly more often than interventional radiologists (98.6% vs. 76.3%; p < .001), but this choice did not appear to be dependent on patient characteristics. Conclusion: In ACST-2, plaque characteristics and severity of stenosis did not primarily determine interventionalists’ choice of stent or use or type of CPD, suggesting that other factors, such as vascular anatomy or personal and centre preference, may be mor...

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30210 - Clinical neurology

Project

—

Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European journal of vascular and endovascular surgery

ISSN

1078-5884

e-ISSN

1532-2165

Volume of the periodical

53

Issue of the periodical within the volume

5

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

617-625

UT code for WoS article

000401678900004

EID of the result in the Scopus database

2-s2.0-85014838339