Calprotectin and calgranulin C serum levels in bacterial sepsis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F19%3AE0107726" target="_blank" >RIV/00843989:_____/19:E0107726 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/19:10396531 RIV/61383082:_____/19:00000496
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0732889318304802?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0732889318304802?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.diagmicrobio.2018.10.006" target="_blank" >10.1016/j.diagmicrobio.2018.10.006</a>
Alternative languages
Result language
angličtina
Original language name
Calprotectin and calgranulin C serum levels in bacterial sepsis
Original language description
The aim of this study was to evaluate the serum levels of calprotectin and calgranulin C and routine biomarkers in patients with bacterial sepsis (BS). The initial serum concentrations of calprotectin and calgranulin C were significantly higher in patients with BS (n = 66) than in those with viral infections (n = 24) and the healthy controls (n = 26); the level of calprotectin was found to be the best predictor of BS, followed by the neutrophil-lymphocyte count ratio (NLCR) and the level of procalcitonin (PCT). The white blood cell (WBC) count and the NLCR rapidly returned to normal levels, whereas PCT levels normalized later and the increased levels of calprotectin, calgranulin C, and C-reactive protein persisted until the end of follow-up. Our results suggest that the serum levels of calprotectin are a reliable biomarker of BS and that the WBC count and the NLCR are rapid predictors of the efficacy of antimicrobial therapy. (C) 2018 Elsevier Inc. All rights reserved.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30102 - Immunology
Result continuities
Project
<a href="/en/project/NV15-30186A" target="_blank" >NV15-30186A: Alarmins in the development and diagnostics of septic complications of tissue injury</a><br>
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Diagnostic microbiology and infectious disease
ISSN
0732-8893
e-ISSN
1879-0070
Volume of the periodical
93
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
219-226
UT code for WoS article
000460196900008
EID of the result in the Scopus database
2-s2.0-85056432107