Impact of cognitive performance and negative symptoms on psychosocial functioning in Czech schizophrenia patients
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F23%3AE0110337" target="_blank" >RIV/00843989:_____/23:E0110337 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11210/23:10466363 RIV/00216208:11110/23:10466363 RIV/00064165:_____/23:10466363
Result on the web
<a href="https://www.nature.com/articles/s41537-023-00374-9" target="_blank" >https://www.nature.com/articles/s41537-023-00374-9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41537-023-00374-9" target="_blank" >10.1038/s41537-023-00374-9</a>
Alternative languages
Result language
angličtina
Original language name
Impact of cognitive performance and negative symptoms on psychosocial functioning in Czech schizophrenia patients
Original language description
Schizophrenia has a profound influence on the real-life functioning of patients. There are several factors inherent to the disease course affecting the level of psychosocial functioning. Our study focused on the impact of cognitive deficit and severity of negative symptoms (i.e., the experiential domain (avolition, asociality, and anhedonia) and the expressive domain (blunted affect and alogia)) to explore psychosocial functioning in schizophrenia. Schizophrenia patients (n = 211) were tested for the presence of cognitive impairment using the NIMH-MATRICS: Measurement and Treatment Research to Improve Cognition in Schizophrenia Consensus Cognitive Cattery (MCCB; MATRICS Consensus Cognitive Battery) and the extent of negative symptoms using the PANSS (PANSS; Positive and Negative Syndrome Scale-selected items). The level of psychosocial functioning was measured with the Personal and Social Performance Scale (PSP). The path analysis using three regression models was used to analyse variables influencing psychosocial functioning (PSP). One of these models analyzed influence of cognitive functioning (MCCB) and negative schizophrenia symptoms (PANSS selected items reflecting expressive and experiential deficits) as predictors and NART/CRT and disease length as confounders. R2 was 0.54. The direct effect of the MCCB (ß = 0.09) on the PSP was suppressed by the strong effect of the negative symptoms (ß = -0.64). The presence of cognitive deficits and negative symptoms in our sample of schizophrenia patients significantly influences the level of their psychosocial functioning, a key factor in remission and recovery.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30215 - Psychiatry
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Schizophrenia
ISSN
2754-6993
e-ISSN
2754-6993
Volume of the periodical
9
Issue of the periodical within the volume
article 43
Country of publishing house
DE - GERMANY
Number of pages
8
Pages from-to
1-8
UT code for WoS article
001031939500001
EID of the result in the Scopus database
2-s2.0-85165246800