Transrectal versus transperineal prostate fusion biopsy: a pair-matched analysis to evaluate accuracy and complications
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F24%3AE0111092" target="_blank" >RIV/00843989:_____/24:E0111092 - isvavai.cz</a>
Alternative codes found
RIV/61988987:17110/24:A2503AE9
Result on the web
<a href="https://link.springer.com/article/10.1007/s00345-024-05245-1" target="_blank" >https://link.springer.com/article/10.1007/s00345-024-05245-1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00345-024-05245-1" target="_blank" >10.1007/s00345-024-05245-1</a>
Alternative languages
Result language
angličtina
Original language name
Transrectal versus transperineal prostate fusion biopsy: a pair-matched analysis to evaluate accuracy and complications
Original language description
Purpose: To evaluate biopsy-related complications and detection rates of any PCa and clinically significant PCa (csPCa, intended as grade group ? 2) between MRI-targeted TP fusion biopsies (TPBx) and TR ones (TRBx). Methods: We performed a multicentric study on 4841 patients who underwent fusion biopsy between 2016 and 2023. A case-control matching was performed to find comparable cohorts of 646 TPBx and 646 TRBx. Mean T test and Pearson chi-square tests were used to compare continuous and categorical variables. Results: Baseline characteristics were comparable between the cohorts, except for target location with a higher rate of anterior lesions in TPBx group. Complications were rare and no difference was found between the groups, with similar rates of infections after TRBx and TPBx (N = 5 (0.8%) vs N = 2 (0.3%), p 0.45). All patients in TRBx and 90.1% in TPBx group received antibiotic prophylaxis. A higher csPCa detection rate was found in TPBx over the group (50.5% vs 36.2%, p < 0.001). On average, positive targeted cores were increased in TPBx group, for any PCa (1.6 vs 1.4, p 0.04) and csPCa (1.0 vs 0.8, p 0.02). Among the limitations of study, we acknowledge the retrospective design and the possible under-reporting of complications. Conclusions: MRI-targeted fusion TPBx achieves a significantly higher csPCa detection than TRBx, with a diagnostic advantage for apical and anterior lesions. No significant differences were found in terms of complications that were rare in both groups, considering a widespread adoption of antibiotic prophylaxis.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30217 - Urology and nephrology
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
World journal of urology
ISSN
0724-4983
e-ISSN
1433-8726
Volume of the periodical
42
Issue of the periodical within the volume
article 535
Country of publishing house
DE - GERMANY
Number of pages
8
Pages from-to
1-8
UT code for WoS article
001326607300001
EID of the result in the Scopus database
2-s2.0-85204906413