Role of alveolar-arterial difference in estimation of extravascular lung water in COVID-19-related ARDS
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F24%3AE0111273" target="_blank" >RIV/00843989:_____/24:E0111273 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/24:00138798 RIV/61988987:17110/24:A2503A8V
Result on the web
<a href="http://rc.rcjournal.com/content/69/12/1548" target="_blank" >http://rc.rcjournal.com/content/69/12/1548</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.4187/respcare.11804" target="_blank" >10.4187/respcare.11804</a>
Alternative languages
Result language
angličtina
Original language name
Role of alveolar-arterial difference in estimation of extravascular lung water in COVID-19-related ARDS
Original language description
BACKGROUND: The dominant feature of COVID-19-associated ARDS is gas exchange impairment. Extravascular lung water index is a surrogate for lung edema and reflects the level of alveolocapillary disruption. The primary aim was the prediction of extravascular lung water index by the alveolar-arterial oxygen difference. The secondary aims were in determining the relationship between the extravascular lung water index and other oxygenation parameters, the FIO2, end-tidal oxygen concentration, pulmonary oxygen gradient (FIO2 minus end-tidal oxygen concentration), and PaO2. METHODS: This observational prospective single-center study was performed at the Department of Anaesthesiology and Intensive Care, The University Hospital in Ostrava, The Czech Republic, during the COVID-19 pandemic, from March 20, 2020, until May 24, 2021. RESULTS: The relationship between the extravascular lung water index and alveolar-arterial oxygen difference showed only a mild-to-moderate correlation (r = 0.33, P < .001). Other extravascular lung water index correlations were as follows: FIO2 (r = 0.33, P < .001), end-tidal oxygen concentration (r = 0.26, P = .0032), FIO2 minus end-tidal oxygen concentration (r = 0.15, P = .0624), and PaO2 (r = –0.15, P = .01). CONCLUSIONS: The alveolar-arterial oxygen difference does not reliably correlate with the extravascular lung water index and the degree of lung edema in COVID-19–associated ARDS.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30221 - Critical care medicine and Emergency medicine
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Respiratory care
ISSN
0020-1324
e-ISSN
1943-3654
Volume of the periodical
69
Issue of the periodical within the volume
12
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
1548-1554
UT code for WoS article
001368986700009
EID of the result in the Scopus database
2-s2.0-85210105809