Application of Vapor Phase Hydrogen Peroxide for Decontamination of Ergot Alkaloids - LC-ESI-MS Study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F18055168%3A_____%2F08%3A%230000010" target="_blank" >RIV/18055168:_____/08:#0000010 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Application of Vapor Phase Hydrogen Peroxide for Decontamination of Ergot Alkaloids - LC-ESI-MS Study

Original language description

The aim of our research is focused on the application of VPHP for decontamination of chemical warfare and biologically active compounds. Ergot alkaloids were the substances under study, which are a wide group of pharmaceutical active compounds. It was study ergopeptines (bromokryptine, ergotamine, dihydroergotamine) together with their semisythetic derivatives (lisuride, pergolide, nicergoline). Our research used several analytical methods (NMR, MS) for characterization of decomposition products. Highlysensitive methods for hyphenated LC/ESI-MS/MS were developed for monitoring of kinetics of decontamination process.

Czech name

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Czech description

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Type

A - Audiovisual production

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2008

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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