Putting gluten back on menu - Safety assessment of polyphenol-rich wheat varieties in Celiac Disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F25328859%3A_____%2F24%3AN0000009" target="_blank" >RIV/25328859:_____/24:N0000009 - isvavai.cz</a>
Result on the web
<a href="https://efsa.onlinelibrary.wiley.com/doi/full/10.2903/j.efsa.2024.e221115" target="_blank" >https://efsa.onlinelibrary.wiley.com/doi/full/10.2903/j.efsa.2024.e221115</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2903/j.efsa.2024.e221115" target="_blank" >10.2903/j.efsa.2024.e221115</a>
Alternative languages
Result language
angličtina
Original language name
Putting gluten back on menu - Safety assessment of polyphenol-rich wheat varieties in Celiac Disease
Original language description
This study provides a comprehensive proteomic and metabolomic analysis of novel anthocyanin- and carotenoid-rich wheat varieties to assess their immunogenicity in the context of Celiac Disease. Using (semi)-quantitative mass spectrometry, the research found that gliadin expression and peptide release, particularly those containing immunostimulatory gamma-gliadin epitopes, vary significantly across different wheat varieties. While non-targeted mass spectrometry provided valuable insights, the study acknowledged potential methodological biases, such limitations of ion current intensity as a measure of peptide abundance. Despite promising results, further research is required to determine the safety and efficacy of coloured wheat varieties for Celiac Disease patients, considering the complex interplay of gluten proteins, food processing, digestion and matrix effects. The ongoing studies hold potential for developing nutritionally beneficial wheat alternatives for Celiac Disease management.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
40401 - Agricultural biotechnology and food biotechnology
Result continuities
Project
<a href="/en/project/QL24010230" target="_blank" >QL24010230: Colored wheat and barley – a challenge for the future</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
EFSA Journal
ISSN
1831-4732
e-ISSN
1831-4732
Volume of the periodical
22
Issue of the periodical within the volume
Special Issue SI
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
e221115
UT code for WoS article
001381139600001
EID of the result in the Scopus database
2-s2.0-85212666857