Pattern of miR-155 and PU.1 expression in CLL/SLL and aggressive lymphomas

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F26424991%3A_____%2F11%3A%230000012" target="_blank" >RIV/26424991:_____/11:#0000012 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Pattern of miR-155 and PU.1 expression in CLL/SLL and aggressive lymphomas

Original language description

We herein found the increased levels of miR-155 coupled with downregulation of its target PU.1 are frequent events in B cells of a vast majority of CLL patients (N=169). To advance understanding of miR-155 and PU.1 in lymphoid malignancies we studied lymph node biopsies derived from patients with lymphomas. We show that increased miR-155 levels are also found in DLBCL (N=31, P < 0.0001), Hodgkin lymphoma (HL, N=22, P < 0.0001), follicular lymphoma (FL, N=23, P < 0.001), small lymphocytic lymphoma (SLL,N=12, P < 0.01), and marginal zone lymphoma (MZL, N=11, P < 0.01).

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

<a href="/en/project/FR-TI2%2F509" target="_blank" >FR-TI2/509: *Development of kit for testing molecular effects of anti-tumor drugs on chromatin structure</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Blood

ISSN

0006-4971

e-ISSN

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Volume of the periodical

118

Issue of the periodical within the volume

21

Country of publishing house

US - UNITED STATES

Number of pages

1

Pages from-to

4600

UT code for WoS article

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EID of the result in the Scopus database

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