Clinical utility of applying a simple, low-cost methodic approach to evaluation of circulating tumor DNA ( ctDNA) in colorectal cancer patients undergoing surgical treatment
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F26475821%3A_____%2F14%3A%230000226" target="_blank" >RIV/26475821:_____/14:#0000226 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Clinical utility of applying a simple, low-cost methodic approach to evaluation of circulating tumor DNA ( ctDNA) in colorectal cancer patients undergoing surgical treatment
Original language description
Poster at UEGWeek 2014 describing low-cost methodic approach to evaluation of circulating tumor DNA in colorectal cancer patients. Circulating tumor DNA (ctDNA) is currently a very promising marker for non-invasive management of patients with cancer. ctDNA consists of short DNA fragments originating from the tumor tissue, which occur freely in the peripheral blood of the patients, predominantly in advanced stages. The main clinical significance of ctDNA , according to recent studies, is in monitoring patients after tumor resection, detection of recurrence or progression of disease and predictingand monitoring the response to treatment. Most methods for ctDNA detection and monitoring are based on highly dedicated technologies (digital PCR with subsequent detection by flow cytometry or next-generation sequencing) and the high cost of equipment as well as sample processing prevents wide application of ctDNA testing in a clinical practice. We present here a routine procedure for the ctDNA
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT13660" target="_blank" >NT13660: Quality evaluation of multimodal treatment in patients with colorectal liver metastatic disease: Mutlicentric study within Czech complex oncology centres</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů