Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre) analytical Work Flows
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F86652036%3A_____%2F20%3A00535750" target="_blank" >RIV/86652036:_____/20:00535750 - isvavai.cz</a>
Result on the web
<a href="https://pure.mpg.de/rest/items/item_3220611_1/component/file_3220612/content" target="_blank" >https://pure.mpg.de/rest/items/item_3220611_1/component/file_3220612/content</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1373/clinchem.2019.306837" target="_blank" >10.1373/clinchem.2019.306837</a>
Alternative languages
Result language
angličtina
Original language name
Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre) analytical Work Flows
Original language description
BACKGROUND: In cancer patients, circulating cell-free DNA (ccfDNA) can contain tumor-derived DNA (ctDNA), which enables noninvasive diagnosis, real-time monitoring, and treatment susceptibility testing. However, ctDNA fractions are highly variable, which challenges downstream applications. Therefore, established preanalytical work flows in combination with cost-efficient and reproducible reference materials for ccfDNA analyses are crucial for analytical validity and subsequently for clinical decision-making.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Clinical Chemistry
ISSN
0009-9147
e-ISSN
1530-8561
Volume of the periodical
66
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
149-160
UT code for WoS article
000514384200027
EID of the result in the Scopus database
2-s2.0-85084993544