Continuous fabrication of braided composite nanofibrous surgical yarns using advanced AC electrospinning and braiding technology
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27283933%3A_____%2F24%3AN0000036" target="_blank" >RIV/27283933:_____/24:N0000036 - isvavai.cz</a>
Alternative codes found
RIV/46747885:24210/24:00012339 RIV/46747885:24410/24:00012339 RIV/46747885:24510/24:00012339 RIV/46747885:24620/24:00012339
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S2452213924001232" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2452213924001232</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.coco.2024.101932" target="_blank" >10.1016/j.coco.2024.101932</a>
Alternative languages
Result language
angličtina
Original language name
Continuous fabrication of braided composite nanofibrous surgical yarns using advanced AC electrospinning and braiding technology
Original language description
Composite nanofibrous yarns (CNY), featuring a submicron electrospun sheath coated on a micro-scale core yarn have gained attention within the academic and industrial communities due to their unique structure. When braided, these CNYs hold great promise as next-generation surgical yarns. However, large-scale production of CNYs using conventional electrospinning techniques remains technologically challenging, and maintaining the integrity of the fibrous sheath during braiding presents further difficulties. Here, we propose a novel approach for continuously fabricating functional braided CNYs using collectorless alternating current (AC) electrospinning and braiding technology. Our approach utilized polycaprolactone-polylactic acid (PCL-PLA) blends and PCL-PLA with chlorhexidine (CHX) or triclosan (TRC) electrospun fibers for the sheath layer, while PLA micro-yarns acted as the core layer. Morphological analyses confirmed the successful fabrication of braided CNYs. Additionally, infrared spectroscopy validated the presence of CHX or TRC in the resulting yarns. The resulting braided CNYs exhibited excellent breaking force (29 N) and thermal stability (270 ◦C). Cytotoxicity and antibacterial assessments demonstrated that CHX-loaded braided CNYs could serve as biocompatible antibacterial surgical sutures. The proposed method offers a versatile approach for producing various functional braided CNYs applicable in tissue engineering scaffolds, filters, wearable electronics, and sensors.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30401 - Health-related biotechnology
Result continuities
Project
<a href="/en/project/EH22_008%2F0004562" target="_blank" >EH22_008/0004562: Excellent Research in Regenerative Medicine</a><br>
Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Composites Communications
ISSN
2452-2139
e-ISSN
—
Volume of the periodical
48
Issue of the periodical within the volume
june 2024
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
nestrankovano
UT code for WoS article
001243377100001
EID of the result in the Scopus database
2-s2.0-85192807207