Pseudohyperkalemia - Potassium released from cells due to clotting and centrifugation - a case report

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27661989%3A_____%2F18%3AN0000004" target="_blank" >RIV/27661989:_____/18:N0000004 - isvavai.cz</a>

Alternative codes found

RIV/61988987:17110/18:A1901RS0

Result on the web

<a href="https://www.biochemia-medica.com/en/journal/28/1/10.11613/BM.2018.011002" target="_blank" >https://www.biochemia-medica.com/en/journal/28/1/10.11613/BM.2018.011002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.11613/BM.2018.011002" target="_blank" >10.11613/BM.2018.011002</a>

Result language

angličtina

Original language name

Pseudohyperkalemia - Potassium released from cells due to clotting and centrifugation - a case report

Original language description

Hyperkalemia is a potentially lethal condition. Pseudohyperkalemia should be always excluded before implementing treatment to prevent inappropriate cause of hypokalemia - equally a potentially lethal condition. Here we present a case report of a 62 year female with chronic myeloproliferative disorder, i.e. essential thrombocythemia. The laboratory test results for potassium concentration were 6.3 mmol/L, for platelet count 1305 x 10(9)/L and for leukocyte count 39.8 x 10(9)/L. This was due to a temporary drug withdrawal after a surgical intervention for gastric bleeding. Potassium concentration in lithium heparin plasma collected in a vacuum tube without gel separator and in whole blood syringe were 4.6 mmol/L and 3.4 mmol/L, respectively. It means that mechanical stress such as centrifugation can contribute to spurious hyperkalemia. Prior to reporting unexpected hyperkalemia result, pseudohyperkalemia should always be considered by the laboratory. Such potassium results require investigation in case it is pseudohyperkalemia, which may be due to thrombocytosis and leukocytosis. In cases where thrombocytosis or leukocytosis exists, an interpretative comment indicating these conditions inserted with the results of the potassium concentration can increase awareness for more accurate patient care decisions.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30200 - Clinical medicine

Project

—

Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biochemia Medica

ISSN

1330-0962

e-ISSN

1846-7482

Volume of the periodical

28

Issue of the periodical within the volume

1

Country of publishing house

HR - CROATIA

Number of pages

5

Pages from-to

011002

UT code for WoS article

000425617200019

EID of the result in the Scopus database

—