Preparation and chemical-physical characterization of porous nanostructured HA scaffold

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44265786%3A_____%2F08%3A13100001" target="_blank" >RIV/44265786:_____/08:13100001 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Preparation and chemical-physical characterization of porous nanostructured HA scaffold

Original language description

The synthetic nanostructured HA powder was prepared by the reaction of calcium hydroxide aqueous solution and phosphoric acid. The powders were foamed using hydrogen peroxide and heat treated at temperatures ranging from 120 to 700°C. Bovine deproteinized bone BioOss was used as a reference material. Elemental analysis, X-ray diffraction, chemical analysis, differential thermal analysis, scanning electron microscopy, gas adsorption and mercury porosimetry were used to characterize the precipitates. In vitro cytotoxicity test and the preclinical evaluation of this material were performed. In vivo tests were carried out in the tibiae of beagle dogs. All animals were euthanized 3 and 6 months after implantation.. The physico-chemical properties of HA granules and in vivo tests determined that synthetic scaffold is comparable with bovine bone material. No significant differences between synthetic HA150 scaffolds and bovine bone BioOss were observed in vivo.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry

OECD FORD branch

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Project

<a href="/en/project/FT-TA3%2F131" target="_blank" >FT-TA3/131: Research on problems of spinal diseases focused on degenerative and post-traumatic states of the spine, applying findings in the tissue engineering, the vertebrae biomechanics, the osseointegration of artificial replacements and their failure revising.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2008

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Clinical Oral Implants Research

ISSN

0905-7161

e-ISSN

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Volume of the periodical

19

Issue of the periodical within the volume

9

Country of publishing house

CH - SWITZERLAND

Number of pages

1

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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