An Effectiveness Evaluation of Information Technology of Gene Expression Profiles Processing for Gene Networks Reconstruction
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13440%2F18%3A43893760" target="_blank" >RIV/44555601:13440/18:43893760 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.5815/ijisa.2018.07.01" target="_blank" >http://dx.doi.org/10.5815/ijisa.2018.07.01</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5815/ijisa.2018.07.01" target="_blank" >10.5815/ijisa.2018.07.01</a>
Alternative languages
Result language
angličtina
Original language name
An Effectiveness Evaluation of Information Technology of Gene Expression Profiles Processing for Gene Networks Reconstruction
Original language description
The paper presents the research results concerning an effectiveness evaluation of information technology of gene expression profiles processing for purpose of gene regulatory networks reconstruction. The information technology is presented as a structural block-chart of step-by-step stages of the studied data processing. The DNA microchips of patients, who were investigated on different types of cancer, were used as experimental data. The optimal parameters of data processing algorithm at appropriate stage of this process implementation by quantity criteria of data processing quality were determined during simulation. Validation of the reconstructed gene networks was performed with the use of ROC-analysis by comparison of character of genes interconnection in both the basic network and networks reconstructed based on the obtained biclusters.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
Result continuities
Project
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Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Intelligent Systems and Applications
ISSN
2074-904X
e-ISSN
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Volume of the periodical
2018
Issue of the periodical within the volume
10(7)
Country of publishing house
CN - CHINA
Number of pages
10
Pages from-to
1-10
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-85049405773