Lyme disease-associated vasculitis with fatal course

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13450%2F23%3A43898551" target="_blank" >RIV/44555601:13450/23:43898551 - isvavai.cz</a>

Result on the web

<a href="https://www.researchgate.net/publication/376871628_Lyme_disease-associated_vasculitis_with_fatal_course" target="_blank" >https://www.researchgate.net/publication/376871628_Lyme_disease-associated_vasculitis_with_fatal_course</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jns.2023.122283" target="_blank" >10.1016/j.jns.2023.122283</a>

Result language

angličtina

Original language name

Lyme disease-associated vasculitis with fatal course

Original language description

Background and aimsSecondary vasculitis of the central nervous system is a rare manifestation of neuroborreliosis. We present the case report of a patient with a fatal course of this disease.MethodsThe case report describes the course of a rare disease. The case concerns a woman, 49 years old. The patient was admitted to the infectious disease department with a diagnosis of suspected neuroborreliosis. The complaints reported were headache, dizziness, diplopia, gait disturbances and lower limbs paresthesia.ResultsThe patient was treated with antibiotics. At clinical progression, CTA showed multiple stenoses and occlusions of intracranial cerebral arteries (occlusions a. basilaris, both vertebral arteries, both anterior cerebral arteries). The picture corresponded to vasculitic changes. On further investigation, no other cause of vasculitic changes was found. Despite significant immunomodulatory therapy (corticoids and cyclophosphamide), there were extensive ischemic changes in the brain tissue with subsequent edema. Anti-edema treatment was administered and a decompressive craniectomy was performed. Edema and ischemic changes continued to progress. Despite maximum therapy, the patient died.ConclusionsSecondary vasculitis of the central nervous system caused by neuroborreliosis is a rare disease. Early initiation of immunomodulation therapy is the only possible procedure. Despite maximum therapy, however, the disease can have a fatal course.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30303 - Infectious Diseases

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of the Neurological Sciences

ISSN

0022-510X

e-ISSN

1878-5883

Volume of the periodical

455

Issue of the periodical within the volume

S

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

1

Pages from-to

20

UT code for WoS article

001163199101594

EID of the result in the Scopus database

—