Metalloenzyme-inspired approach to the design and applications of phosphatase-mimetic nanozymes. Bridging the inorganic and organic worlds
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13520%2F24%3A43898985" target="_blank" >RIV/44555601:13520/24:43898985 - isvavai.cz</a>
Result on the web
<a href="https://pubs.rsc.org/en/content/articlelanding/2024/en/d4en00144c" target="_blank" >https://pubs.rsc.org/en/content/articlelanding/2024/en/d4en00144c</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/d4en00144c" target="_blank" >10.1039/d4en00144c</a>
Alternative languages
Result language
angličtina
Original language name
Metalloenzyme-inspired approach to the design and applications of phosphatase-mimetic nanozymes. Bridging the inorganic and organic worlds
Original language description
Nanozymes were introduced approximately 15 years ago as inorganic materials capable of mimicking the catalytic abilities of natural (protein-based) enzymes. While the catalytic efficiency of nanozymes typically does not match that of enzymes, their research gains special attention due to their potential advantages over conventional enzymes, particularly their higher resistance to adverse conditions. This article focuses on the utilization of cerium oxide for the catalytic acceleration of non-redox reactions (e.g., dephosphorylation). It elucidates certain analogies between the functioning of conventional enzymes (metalloenzymes) and the nanozymatic activity of ceria, and the distinctions in the mechanisms of action between the two catalyst types. The unique catalytic (enzymatic) ability of cerium oxide is predetermined by the fine interplay between surface reactivity (associated with surface defects) and structural integrity (simplicity and stability of the subsurface crystalline structure). Limitations associated with the less flexible nature of cerium oxide are discussed, together with strategies to overcome them, which are based on the new concept of dynamic active sites. Possible generalizations to other metal oxide-based nanozymes are briefly mentioned.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
21001 - Nano-materials (production and properties)
Result continuities
Project
<a href="/en/project/LM2015073" target="_blank" >LM2015073: Nanomaterials and Nanotechnologies for Environment Protection and Sustainable Future</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Environmental Science-Nano
ISSN
2051-8153
e-ISSN
2051-8161
Volume of the periodical
11
Issue of the periodical within the volume
8
Country of publishing house
GB - UNITED KINGDOM
Number of pages
17
Pages from-to
3268-3285
UT code for WoS article
001251311300001
EID of the result in the Scopus database
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