DEVELOPMENT OF FIBROUS IMPLANT FOR THE TREATMENT OF GLAUCOMA

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24210%2F16%3A00003880" target="_blank" >RIV/46747885:24210/16:00003880 - isvavai.cz</a>

Alternative codes found

RIV/46747885:24410/16:00003880

Result on the web

<a href="http://www.nanocon.eu" target="_blank" >http://www.nanocon.eu</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

DEVELOPMENT OF FIBROUS IMPLANT FOR THE TREATMENT OF GLAUCOMA

Original language description

This article deals with the development of fibrous non-biodegradable drainage device for the treatment of glaucoma disease. Currently produced implants are often associated with hypotony, undesired fibrosis, tissue damages around the implant and many others [1]. Nanofiber implant has great potential to alleviate or completely eliminate these problems. The main goal of this work was a creation of the drain for safety drainage of intraocular fluid from the patient eye to achieve a normal intraocular pressure. The small-diameter tubular implant (<1 mm) was developed by the use of the electrospinning technology. The structure was composed of two parts, by using special types of collectors. The outer part was formed of non-biodegradable material that is resistant to cell growth. The inner supporting part was formed of hydrophilic material which is also resistant to cell growth. This part prevents the compression of the outer material and a total blockage of the drain. The special structure supports the drainage of fluid. Material was subjected to morphological structures, liquid transport tests and in-vitro cell adhesion tests. First results show great potential in the use of the implant in treatment of glaucoma disease.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

JJ - Other materials

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

NANOCON 2016 - Conference Proceedings, 8th International Conference on Nanomaterials - Research and Application

ISBN

9788087294710

ISSN

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e-ISSN

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Number of pages

6

Pages from-to

497-502

Publisher name

TANGER spol. s r.o.

Place of publication

Ostrava

Event location

Brno

Event date

Jan 1, 2016

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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