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Long-term comparative study of the stability of nanofibrous materials from biodegradable polycaprolactone for skin wound dressing

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24210%2F24%3A00011770" target="_blank" >RIV/46747885:24210/24:00011770 - isvavai.cz</a>

  • Alternative codes found

    RIV/46747885:24410/24:00011770 RIV/46747885:24510/24:00011770 RIV/46747885:24620/24:00011770

  • Result on the web

    <a href="https://doi.org/10.37904/nanocon.2023.4792" target="_blank" >https://doi.org/10.37904/nanocon.2023.4792</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.37904/nanocon.2023.4792" target="_blank" >10.37904/nanocon.2023.4792</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Long-term comparative study of the stability of nanofibrous materials from biodegradable polycaprolactone for skin wound dressing

  • Original language description

    This study deals with a long-term stability study of biodegradable polycaprolactone (PCL) nanofibrous dressings for skin applications, an important parameter for the storage of materials prior to actual application. Nanofibrous materials generally have suitable properties for regenerative medicine and tissue engineering, such as high porosity with small pore size, high areal density of fibers, large specific surface area, and these materials are able to mimic natural skin extracellular matrix with their fibrous structure. These properties allow nanofibrous dressings to provide the required protection to damaged tissues while promoting the wound-healing process. However, the issue of their long-term stability and degradation behaviour is still under investigation. The aim of this study was to observe and compare the long-term stability of electrospun PCL nanofibrous dressings exposed to different storage conditions. The study focused on the effect of nanofibrous material parameters, which included the surface weight; the solvent system used during the preparation of the polymeric spinning solutions and last but not least, the effect of ethylene oxide sterilization on the stability of the nanofibrous planar dressing over a period of 6-12 months.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    21001 - Nano-materials (production and properties)

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    CONFERENCE PROCEEDINGS - NANOCON 2023

  • ISBN

    978-80-88365-13-6

  • ISSN

    2694-930X

  • e-ISSN

  • Number of pages

    10

  • Pages from-to

    303-312

  • Publisher name

    Tanger Ltd.

  • Place of publication

    Ostrava

  • Event location

    Brno

  • Event date

    Jan 1, 2023

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article

    001234125400049