Importance and necessity of the surface modification of nylon 6 films for future biomedical application
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24220%2F16%3A00004385" target="_blank" >RIV/46747885:24220/16:00004385 - isvavai.cz</a>
Alternative codes found
RIV/46747885:24510/16:00004385 RIV/46747885:24620/16:00004385
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Importance and necessity of the surface modification of nylon 6 films for future biomedical application
Original language description
Polyamide plays an important role in biomedical application such as suture material, coated textile against skin infection, wound dressing, catheters and bone tissue scaffolds. Surface modification of polyamide is very crucial factor to improve its performances by imparting desirable biomaterial properties. This report is focused on the efficient reduction of amide functional groups to secondary amine on Nylon 6 film surface with borane-tetrahydrofuran (BH3-THF) complex, followed by further alkylation. More precisely, we have studied the reaction of benzyl chloride (C6H5CH2Cl) in presence of potassium tert-butoxide (t-BuOK) on the modified Nylon 6 films. Thus, introduction of benzyl group to secondary amine of modified Nylon 6 has been accomplished. This type of transformation is expected to be generally applicable for functionalization of almost any polyamide. By using different alkylation reactions we will be able to tune the surface properties of polymers obtained for almost any applications. We also hope that polymers thus obtained will be biocompatible. The surface modifications were confirmed by both non-spectral methods and spectroscopic as well as microscopic analyses. Water contact angle (WCA) and free surface energy (FSE) measurements indicated the significant change in surface morphology that were established by X-ray photoelectron spectroscopy (XPS), Fourier-transform infrared spectroscopy (FT-IR), Raman spectroscopy and atomic force microscopy (AFM). We are firmly convinced of the future prospect for further surface modification of these functionalized nylon 6 films with high potential in the field of biomedical application.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
<a href="/en/project/LO1201" target="_blank" >LO1201: DEVELOPMENT OF THE INSTITUTE FOR NANOMATERIALS, ADVANCED TECHNOLOGIES AND INNOVATION</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
NANOCON 2016 - Conference Proceedings, 8th International Conference on Nanomaterials - Research and Application
ISBN
978-80-87294-71-0
ISSN
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e-ISSN
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Number of pages
6
Pages from-to
663-668
Publisher name
TANGER LTD, KELTICKOVA 62, SLEZSKA, OSTRAVA 710 00, CZECH REPUBLIC
Place of publication
Ostrava
Event location
Brno
Event date
Jan 1, 2016
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000410656100115