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Importance and necessity of the surface modification of nylon 6 films for future biomedical application

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24220%2F16%3A00004385" target="_blank" >RIV/46747885:24220/16:00004385 - isvavai.cz</a>

  • Alternative codes found

    RIV/46747885:24510/16:00004385 RIV/46747885:24620/16:00004385

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Importance and necessity of the surface modification of nylon 6 films for future biomedical application

  • Original language description

    Polyamide plays an important role in biomedical application such as suture material, coated textile against skin infection, wound dressing, catheters and bone tissue scaffolds. Surface modification of polyamide is very crucial factor to improve its performances by imparting desirable biomaterial properties. This report is focused on the efficient reduction of amide functional groups to secondary amine on Nylon 6 film surface with borane-tetrahydrofuran (BH3-THF) complex, followed by further alkylation. More precisely, we have studied the reaction of benzyl chloride (C6H5CH2Cl) in presence of potassium tert-butoxide (t-BuOK) on the modified Nylon 6 films. Thus, introduction of benzyl group to secondary amine of modified Nylon 6 has been accomplished. This type of transformation is expected to be generally applicable for functionalization of almost any polyamide. By using different alkylation reactions we will be able to tune the surface properties of polymers obtained for almost any applications. We also hope that polymers thus obtained will be biocompatible. The surface modifications were confirmed by both non-spectral methods and spectroscopic as well as microscopic analyses. Water contact angle (WCA) and free surface energy (FSE) measurements indicated the significant change in surface morphology that were established by X-ray photoelectron spectroscopy (XPS), Fourier-transform infrared spectroscopy (FT-IR), Raman spectroscopy and atomic force microscopy (AFM). We are firmly convinced of the future prospect for further surface modification of these functionalized nylon 6 films with high potential in the field of biomedical application.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    10404 - Polymer science

Result continuities

  • Project

    <a href="/en/project/LO1201" target="_blank" >LO1201: DEVELOPMENT OF THE INSTITUTE FOR NANOMATERIALS, ADVANCED TECHNOLOGIES AND INNOVATION</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    NANOCON 2016 - Conference Proceedings, 8th International Conference on Nanomaterials - Research and Application

  • ISBN

    978-80-87294-71-0

  • ISSN

  • e-ISSN

  • Number of pages

    6

  • Pages from-to

    663-668

  • Publisher name

    TANGER LTD, KELTICKOVA 62, SLEZSKA, OSTRAVA 710 00, CZECH REPUBLIC

  • Place of publication

    Ostrava

  • Event location

    Brno

  • Event date

    Jan 1, 2016

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article

    000410656100115