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leInfluence of Electrospinning Parameters on the Hydrophilicity of Electrospun Polycaprolactone Nanofibres

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F19%3A00006635" target="_blank" >RIV/46747885:24410/19:00006635 - isvavai.cz</a>

  • Alternative codes found

    RIV/46747885:24620/19:00006635

  • Result on the web

    <a href="https://www.ingentaconnect.com/content/asp/jnn/2019/00000019/00000011/art00048" target="_blank" >https://www.ingentaconnect.com/content/asp/jnn/2019/00000019/00000011/art00048</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1166/jnn.2019.16605" target="_blank" >10.1166/jnn.2019.16605</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    leInfluence of Electrospinning Parameters on the Hydrophilicity of Electrospun Polycaprolactone Nanofibres

  • Original language description

    In the present study, PCL (polycaprolactone) nanofibres were produced by the electrospinning method. The use of PCL electrospun biopolymer in biomedical applications has attracted considerable interest due to its chemical resistance, biodegradability, biocompatibility, and non-toxic characteristics. However, the hydrophobic nature of PCL polymer restricts the useage of PCL nanofibres for the cell adhesion and absorption. A hydrophilic and biocompatible PCL electrospun mat with a low water contact angle is an attractive strategy for development in tissue engineering and wound dressing. In this study, we demonstrate a feasible and simple method to produce hydrophilic PCL nanofibres for possible application in wound dressing. Chloroform/ethanol (EtOH) and chloroform/dimethylformamide (DMF) mixtures were used as two different solvent systems. The impact of the polymeric solution concentration, applied voltage, and solvent mixtures on the fibre surface morphology and water contact angle was investigated. Consequently, bead structures were observed at low concentrations but disappeared with increases in the concentration. It was observed that the size of beads decreased and the diameter of fibres increased with increasing voltage. The wettability of the webs changed from hydrophobic to hydrophilic with changes of the polymer concentration. The contact angle of the nanofibre mats decreased in both solvent systems as the concentration increased. The results showed that the lowest contact angle was obtained in 24% wt. PCL chloroform/EtOH solution and was 68°. The highest contact angle was obtained in 4% wt. PCL chloroform/EtOH solution and was 112°. Using this method, the surface hydrophilicity of the PCL nanofibres improved easily without any surface treatment.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    21001 - Nano-materials (production and properties)

Result continuities

  • Project

    <a href="/en/project/EF16_019%2F0000843" target="_blank" >EF16_019/0000843: Hybrid Materials for Hierarchical Structure</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Nanoscience and Nanotechnology

  • ISSN

    1533-4880

  • e-ISSN

  • Volume of the periodical

    19

  • Issue of the periodical within the volume

    11

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    10

  • Pages from-to

    7251-7260

  • UT code for WoS article

    000475752300047

  • EID of the result in the Scopus database