Novel double-layered planar scaffold combining electrospun PCL fibers and PVA hydrogels with high shape integrity and water stability
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F20%3A00006987" target="_blank" >RIV/46747885:24410/20:00006987 - isvavai.cz</a>
Alternative codes found
RIV/46747885:24510/20:00006987
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0167577X19319135" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0167577X19319135</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.matlet.2019.127281" target="_blank" >10.1016/j.matlet.2019.127281</a>
Alternative languages
Result language
angličtina
Original language name
Novel double-layered planar scaffold combining electrospun PCL fibers and PVA hydrogels with high shape integrity and water stability
Original language description
Novel double-layered materials with different properties of each side were prepared via needleless electrospinning and compared in terms of morphology, wettability, adhesion and proliferation of mouse fibroblasts. The materials consist of hydrophilic poly(vinyl alcohol) fibers with low (PVA_L) or high (PVA_H) degree of hydrolysis, and hydrophobic poly(ε-caprolactone) (PCL) fibrous layer. Although the PVA_L fibers were fully dissolved following a water exposure, the shape of the scaffold was maintained due to water stable PCL layer. Exposing PVA_H based fibrous layer to water created a hydrogel-like structure with shape defined by the PCL layer. According to the MTT assay, the mouse fibroblasts seeded on the scaffold exhibited the greatest proliferative activity on the PCL fibers. These double-layered scaffolds with different features on each side are very promising for many novel medical applications such as wound dressing or abdominal adhesion prevention. Article in Materials Letters (Volume 263). Funding received from SGS project Reg. No. 21311.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
21001 - Nano-materials (production and properties)
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Materials Letters
ISSN
0167-577X
e-ISSN
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Volume of the periodical
263
Issue of the periodical within the volume
March
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
4
Pages from-to
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UT code for WoS article
000513952500073
EID of the result in the Scopus database
2-s2.0-85077276366