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AC electrospinning: impact of high voltage and solvent on the electrospinnability and productivity of polycaprolactone electrospun nanofibrous scaffolds

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F22%3A00009888" target="_blank" >RIV/46747885:24410/22:00009888 - isvavai.cz</a>

  • Alternative codes found

    RIV/46747885:24510/22:00009888 RIV/46747885:24620/22:00009888

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S2468519422002543#ack0010" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2468519422002543#ack0010</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.mtchem.2022.101025" target="_blank" >10.1016/j.mtchem.2022.101025</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    AC electrospinning: impact of high voltage and solvent on the electrospinnability and productivity of polycaprolactone electrospun nanofibrous scaffolds

  • Original language description

    Electrospinning technology employs direct current high voltage to produce electrospun fibers from the polymeric liquid or melt. However, until now, the impact of alternating current (AC) high voltage on the spinnability of polymers remains inadequately explored. This work studies the effects of various less toxic solvents and AC high voltage (25 and 32 kVRMS) on the spinnability, morphology, and productivity of polycaprolactone (PCL) electrospun nanofibrous scaffolds (ENS). Besides this, cellular activity on various PCL ENS is also evaluated. Herein, formic acid (F), formic acid/acetic acid (FA), and formic acid/acetic acid/acetone (FAA) solvent systems are used to prepare various concentrations of PCL solutions. Preliminary polymer–solvent interaction studies confirm that FAA is the better solvent choice for PCL than FA and F. FAA-PCL exhibits higher viscosity than FA-PCL and F-PCL due to better polymer–solvent interactions and PCL stability. Consequently, FAA-PCL shows higher electrospun nanofiber productivity at 32 kVRMS (12.4 ± 0.3 g/h), followed by FA-PCL (6.9 ± 0.1 g/h) and F-PCL (2.2 ± 0.2 g/h). Finally, the cytotoxicity and in vitro experiments indicate that the fabricated ENS are noncytotoxic and biocompatible with 3T3-L1 mouse fibroblast cells. This study will inspire the academic and industrial communities to fabricate various polymeric nanofibers on a large scale using AC electrospinning technique.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    20500 - Materials engineering

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Materials Today Chemistry

  • ISSN

    2468-5194

  • e-ISSN

  • Volume of the periodical

    26

  • Issue of the periodical within the volume

    DEC

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    14

  • Pages from-to

  • UT code for WoS article

    000835707200011

  • EID of the result in the Scopus database

    2-s2.0-85133429415