AC electrospinning: impact of high voltage and solvent on the electrospinnability and productivity of polycaprolactone electrospun nanofibrous scaffolds
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F22%3A00009888" target="_blank" >RIV/46747885:24410/22:00009888 - isvavai.cz</a>
Alternative codes found
RIV/46747885:24510/22:00009888 RIV/46747885:24620/22:00009888
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S2468519422002543#ack0010" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2468519422002543#ack0010</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.mtchem.2022.101025" target="_blank" >10.1016/j.mtchem.2022.101025</a>
Alternative languages
Result language
angličtina
Original language name
AC electrospinning: impact of high voltage and solvent on the electrospinnability and productivity of polycaprolactone electrospun nanofibrous scaffolds
Original language description
Electrospinning technology employs direct current high voltage to produce electrospun fibers from the polymeric liquid or melt. However, until now, the impact of alternating current (AC) high voltage on the spinnability of polymers remains inadequately explored. This work studies the effects of various less toxic solvents and AC high voltage (25 and 32 kVRMS) on the spinnability, morphology, and productivity of polycaprolactone (PCL) electrospun nanofibrous scaffolds (ENS). Besides this, cellular activity on various PCL ENS is also evaluated. Herein, formic acid (F), formic acid/acetic acid (FA), and formic acid/acetic acid/acetone (FAA) solvent systems are used to prepare various concentrations of PCL solutions. Preliminary polymer–solvent interaction studies confirm that FAA is the better solvent choice for PCL than FA and F. FAA-PCL exhibits higher viscosity than FA-PCL and F-PCL due to better polymer–solvent interactions and PCL stability. Consequently, FAA-PCL shows higher electrospun nanofiber productivity at 32 kVRMS (12.4 ± 0.3 g/h), followed by FA-PCL (6.9 ± 0.1 g/h) and F-PCL (2.2 ± 0.2 g/h). Finally, the cytotoxicity and in vitro experiments indicate that the fabricated ENS are noncytotoxic and biocompatible with 3T3-L1 mouse fibroblast cells. This study will inspire the academic and industrial communities to fabricate various polymeric nanofibers on a large scale using AC electrospinning technique.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20500 - Materials engineering
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Materials Today Chemistry
ISSN
2468-5194
e-ISSN
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Volume of the periodical
26
Issue of the periodical within the volume
DEC
Country of publishing house
GB - UNITED KINGDOM
Number of pages
14
Pages from-to
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UT code for WoS article
000835707200011
EID of the result in the Scopus database
2-s2.0-85133429415