Synthesis of cyclodextrin-pyrrole conjugates possessing tuneable carbon linkers

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24620%2F18%3A00005612" target="_blank" >RIV/46747885:24620/18:00005612 - isvavai.cz</a>

Result on the web

<a href="https://link.springer.com/article/10.1007/s10847-018-0854-5" target="_blank" >https://link.springer.com/article/10.1007/s10847-018-0854-5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10847-018-0854-5" target="_blank" >10.1007/s10847-018-0854-5</a>

Result language

angličtina

Original language name

Synthesis of cyclodextrin-pyrrole conjugates possessing tuneable carbon linkers

Original language description

Cyclodextrins are naturally occurring cyclic oligosaccharides consisting of glucose units. The main feature of cyclodextrins is the ability to accommodate various lipophilic compounds in their interior, which determines them to be popular helpers to the mankind. However, there is still a demand for new derivatives for advanced applications. Herein, we report the synthesis of β-cyclodextrin–pyrrole conjugates. Their preparation is based on an amide bond formation or copper(I)-catalysed azide-alkyne cycloaddition between β-cyclodextrin and pyrrole derivatives. The main advantage of the synthetic approach lies in the possibility to attach the substituent in β-position, because polypyrroles possessing a substituent in this position are generally more conductive than the N-substituted ones. Moreover, the presented synthetic route is general and allows tuning the properties (various types of connections and lengths) of a linker. The presented cyclodextrin–pyrrole derivatives thus open the door for new applications in the field of sensors or tissue engineering.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10401 - Organic chemistry

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Inclusion Phenomena and Macrocyclic Chemistry

ISSN

1388-3127

e-ISSN

—

Volume of the periodical

92

Issue of the periodical within the volume

3-4

Country of publishing house

CH - SWITZERLAND

Number of pages

8

Pages from-to

339-346

UT code for WoS article

000451049300010

EID of the result in the Scopus database

2-s2.0-85056998295