A Perspective on the Potential Impact of Microplastics and Nanoplastics on the Human Central Nervous System
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24620%2F25%3A00013038" target="_blank" >RIV/46747885:24620/25:00013038 - isvavai.cz</a>
Result on the web
<a href="https://pubs.rsc.org/en/content/articlelanding/2025/en/d4en01017e" target="_blank" >https://pubs.rsc.org/en/content/articlelanding/2025/en/d4en01017e</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/d4en01017e" target="_blank" >10.1039/d4en01017e</a>
Alternative languages
Result language
angličtina
Original language name
A Perspective on the Potential Impact of Microplastics and Nanoplastics on the Human Central Nervous System
Original language description
Humans are constantly exposed to microplastics and nanoplastics (MNPs). Although significant gaps remain in our understanding of their adverse effects on human health, it is increasingly evident that MNPs can penetrate physiological barriers and accumulate in various locations within the human body. Analytical limitations in tracking and measuring nanoplastics in physiological media may persist for several years before we can accurately detect these particles in the human body and establish a clear link between exposure to them and associated hazards. In addition to the few studies that have emerged recently, our knowledge of chemicals with properties similar to those of MNPs, as well as other types of nanomaterials, suggests that MNPs may cross the blood-brain barrier (BBB) and potentially induce damage to the human central nervous system. Here, we provide an overview of the limited number of studies available on this topic and present a perspective on the potential pathways through which MNPs may penetrate the BBB. We also discuss the main mechanisms by which MNPs could potentially impact the central nervous system (CNS), with a focus on neurodegenerative diseases such as Alzheimer‘s disease (AD), Parkinson‘s disease (PD), multiple sclerosis (MS), and amyotrophic lateral sclerosis (ALS). This information could contribute to the development of tailored studies exploring the negative effects of MNPs on the CNS.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10400 - Chemical sciences
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
ENVIRONMENTAL SCIENCE-NANO>
ISSN
2051-8153
e-ISSN
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Volume of the periodical
12
Issue of the periodical within the volume
3
Country of publishing house
GB - UNITED KINGDOM
Number of pages
12
Pages from-to
1809-1820
UT code for WoS article
001416545400001
EID of the result in the Scopus database
2-s2.0-105001086794